位置:首页 > 蛋白库 > IOJAP_HAEIN
IOJAP_HAEIN
ID   IOJAP_HAEIN             Reviewed;         102 AA.
AC   P44471;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Ribosomal silencing factor RsfS {ECO:0000255|HAMAP-Rule:MF_01477};
GN   Name=rsfS {ECO:0000255|HAMAP-Rule:MF_01477}; OrderedLocusNames=HI_0034;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Functions as a ribosomal silencing factor. Interacts with
CC       ribosomal protein L14 (rplN), blocking formation of intersubunit bridge
CC       B8. Prevents association of the 30S and 50S ribosomal subunits and the
CC       formation of functional ribosomes, thus repressing translation.
CC       {ECO:0000255|HAMAP-Rule:MF_01477}.
CC   -!- SUBUNIT: Interacts with ribosomal protein L14 (rplN).
CC       {ECO:0000255|HAMAP-Rule:MF_01477}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01477}.
CC   -!- SIMILARITY: Belongs to the Iojap/RsfS family. {ECO:0000255|HAMAP-
CC       Rule:MF_01477}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L42023; AAC21712.1; -; Genomic_DNA.
DR   PIR; H64140; H64140.
DR   RefSeq; NP_438207.1; NC_000907.1.
DR   RefSeq; WP_005635481.1; NC_000907.1.
DR   AlphaFoldDB; P44471; -.
DR   SMR; P44471; -.
DR   STRING; 71421.HI_0034; -.
DR   EnsemblBacteria; AAC21712; AAC21712; HI_0034.
DR   KEGG; hin:HI_0034; -.
DR   PATRIC; fig|71421.8.peg.34; -.
DR   eggNOG; COG0799; Bacteria.
DR   HOGENOM; CLU_092688_6_1_6; -.
DR   OMA; VVHVFQK; -.
DR   PhylomeDB; P44471; -.
DR   BioCyc; HINF71421:G1GJ1-34-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043023; F:ribosomal large subunit binding; IBA:GO_Central.
DR   GO; GO:0042256; P:mature ribosome assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0090071; P:negative regulation of ribosome biogenesis; IBA:GO_Central.
DR   GO; GO:0017148; P:negative regulation of translation; IBA:GO_Central.
DR   Gene3D; 3.30.460.10; -; 1.
DR   HAMAP; MF_01477; Iojap_RsfS; 1.
DR   InterPro; IPR004394; Iojap/RsfS/C7orf30.
DR   InterPro; IPR043519; NT_sf.
DR   PANTHER; PTHR21043; PTHR21043; 1.
DR   SUPFAM; SSF81301; SSF81301; 1.
DR   TIGRFAMs; TIGR00090; rsfS_iojap_ybeB; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Repressor; Translation regulation.
FT   CHAIN           1..102
FT                   /note="Ribosomal silencing factor RsfS"
FT                   /id="PRO_0000168677"
SQ   SEQUENCE   102 AA;  11386 MW;  BB84F9E4F385B5B7 CRC64;
     MALVEFLMET LDGLKGTDIV HFDVRGKSSI TDNMIICTGT SSRQVSAMAD NLITECKKAG
     FETFGEEGKN TADWIVVDLG QAIVHIMQRD AREMYQLEKL WA
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024