ID   IORB_PYRHO              Reviewed;         202 AA.
AC   O58496;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Indolepyruvate oxidoreductase subunit IorB;
DE            Short=IOR;
DE            EC=1.2.7.8;
DE   AltName: Full=Indolepyruvate ferredoxin oxidoreductase subunit beta;
GN   Name=iorB; OrderedLocusNames=PH0764;
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA   Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
CC   -!- FUNCTION: Catalyzes the ferredoxin-dependent oxidative decarboxylation
CC       of arylpyruvates. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] =
CC         (indol-3-yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-
CC         [ferredoxin]; Xref=Rhea:RHEA:12645, Rhea:RHEA-COMP:10000, Rhea:RHEA-
CC         COMP:10001, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:17640,
CC         ChEBI:CHEBI:33737, ChEBI:CHEBI:33738, ChEBI:CHEBI:57271,
CC         ChEBI:CHEBI:57287; EC=1.2.7.8;
CC   -!- SUBUNIT: Heterodimer of the IorA and IorB subunits.
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DR   EMBL; BA000001; BAA29855.1; -; Genomic_DNA.
DR   PIR; E71124; E71124.
DR   RefSeq; WP_010884855.1; NC_000961.1.
DR   AlphaFoldDB; O58496; -.
DR   SMR; O58496; -.
DR   IntAct; O58496; 1.
DR   MINT; O58496; -.
DR   STRING; 70601.3257172; -.
DR   EnsemblBacteria; BAA29855; BAA29855; BAA29855.
DR   GeneID; 1443090; -.
DR   KEGG; pho:PH0764; -.
DR   eggNOG; arCOG01602; Archaea.
DR   OMA; HGMSQRF; -.
DR   OrthoDB; 120779at2157; -.
DR   Proteomes; UP000000752; Chromosome.
DR   GO; GO:0043805; F:indolepyruvate ferredoxin oxidoreductase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.920.10; -; 1.
DR   InterPro; IPR017719; Indolepyruvate_Fd_OxRdtase_bsu.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR   InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR   Pfam; PF01558; POR; 1.
DR   SUPFAM; SSF53323; SSF53323; 1.
DR   TIGRFAMs; TIGR03334; IOR_beta; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..202
FT                   /note="Indolepyruvate oxidoreductase subunit IorB"
FT                   /id="PRO_0000099935"
SQ   SEQUENCE   202 AA;  21810 MW;  E430872F6F4FF9EE CRC64;
     MKEYNIVITG VGGQGILTAA NLLGWAALKA GYKVRVGEVH GMSQRFGSVI AYVRFGDDVY
     GAMVPEGKAD VILSFEPVEA LRYINYLKKG GLVFTNARPI PPVQVSMGLA TYPSLEEIKR
     IVEEEFNGKF LAFDAEKLAI EAGNVITTNV VLIGALTQTP GFPLSAEHVK EVIRLSVPPK
     AVDVNMKAFD LGVKAAKEML NL