IORF_CVM3
ID IORF_CVM3 Reviewed; 207 AA.
AC P69615; P18453; P18456;
DT 29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 29-MAR-2005, sequence version 1.
DT 29-SEP-2021, entry version 35.
DE RecName: Full=Protein I;
DE AltName: Full=Accessory protein N2;
DE AltName: Full=N internal ORF protein;
DE Short=IORF;
DE AltName: Full=Protein in nucleocapsid ORF;
GN Name=N; Synonyms=I; ORFNames=7b;
OS Murine coronavirus (strain 3) (MHV-3) (Murine hepatitis virus).
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
OC Betacoronavirus; Embecovirus.
OX NCBI_TaxID=11140;
OH NCBI_TaxID=10090; Mus musculus (Mouse).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2171216; DOI=10.1016/0042-6822(90)90316-j;
RA Parker M.M., Masters P.S.;
RT "Sequence comparison of the N genes of five strains of the coronavirus
RT mouse hepatitis virus suggests a three domain structure for the
RT nucleocapsid protein.";
RL Virology 179:463-468(1990).
CC -!- FUNCTION: Structural protein that is not essential for the viral
CC replication either in tissue culture or in its natural host.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}.
CC -!- MISCELLANEOUS: The gene encoding this protein is included within the N
CC gene (alternative ORF).
CC -!- SIMILARITY: Belongs to the coronavirus I protein family. {ECO:0000305}.
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DR EMBL; M35254; AAA46445.1; -; Genomic_RNA.
DR PIR; F45340; F45340.
DR CDD; cd21662; embe-CoV_Protein-I_like; 1.
DR InterPro; IPR004876; Corona_nucI.
DR InterPro; IPR044311; N2-like_embe-CoV.
DR Pfam; PF03187; Corona_I; 1.
PE 3: Inferred from homology;
KW Virion.
FT CHAIN 1..207
FT /note="Protein I"
FT /id="PRO_0000106123"
SQ SEQUENCE 207 AA; 22617 MW; 70DC87B8D06C3192 CRC64;
MESSRRPLGL TKPSVDQIIK IEAEGISQSR LQLLNPTPGV WFPITPGFLA LPSSKRERSF
SLQKDKECLL PMESPLQSKR DIGIDTTAVL LKHLMGSRSN YCPDGIFTIL AQGPMLEPVM
ETALKESSGL QTAKRTPIPA LILSKGTQAV MRLFLLGLRP ARYCLRAFML KALEGLHLLA
DLVRGHNPVG QIIALEAVPT SASLPLL