IORF_CVMJH
ID IORF_CVMJH Reviewed; 207 AA.
AC P0C5A5;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 1.
DT 03-AUG-2022, entry version 33.
DE RecName: Full=Protein I;
DE AltName: Full=N internal ORF protein;
DE Short=IORF;
DE AltName: Full=N2 protein;
DE AltName: Full=Protein in nucleocapsid ORF;
GN Name=I; ORFNames=7b;
OS Murine coronavirus (strain JHM) (MHV-JHM) (Murine hepatitis virus).
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
OC Betacoronavirus; Embecovirus.
OX NCBI_TaxID=11144;
OH NCBI_TaxID=10090; Mus musculus (Mouse).
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=6308569; DOI=10.1093/nar/11.15.5045;
RA Skinner M.A., Siddell S.G.;
RT "Coronavirus JHM: nucleotide sequence of the mRNA that encodes nucleocapsid
RT protein.";
RL Nucleic Acids Res. 11:5045-5054(1983).
CC -!- FUNCTION: Structural protein that is not essential for the viral
CC replication either in tissue culture or in its natural host.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}.
CC -!- MISCELLANEOUS: The gene encoding this protein is included within the N
CC gene (alternative ORF).
CC -!- SIMILARITY: Belongs to the coronaviruses I protein family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=X00990; Type=Miscellaneous discrepancy; Note=The submitted sequence has a stop codon in position 17, but this could be due to a sequencing error or to the presence of quasispecies mutations.; Evidence={ECO:0000305};
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DR EMBL; X00990; -; NOT_ANNOTATED_CDS; mRNA.
DR Proteomes; UP000007193; Genome.
DR CDD; cd21662; embe-CoV_Protein-I_like; 1.
DR InterPro; IPR004876; Corona_nucI.
DR InterPro; IPR044311; N2-like_embe-CoV.
DR Pfam; PF03187; Corona_I; 1.
PE 2: Evidence at transcript level;
KW Virion.
FT CHAIN 1..207
FT /note="Protein I"
FT /id="PRO_0000296312"
SQ SEQUENCE 207 AA; 22829 MW; 39FBB637D7544FCC CRC64;
MESSRRPLGL TKPSAGXIIK IEAERISPSR LQLLNPIPGV WFPITLGFRA LPNSRREKSF
SLHKDKECLL PMESQLHSKR DIGTDTTDVP LKHLMASRSS YCPDGIFTIL EQGPMLAQSM
ATISKELSGS QANRPRLGPL PILLKGTQVA MRLFLLGLRP VRYCLKVFML KAQEGLHLLV
DLVRGHNPVG QIIALEAVPT SASLPLL