IOVO_CARPF
ID IOVO_CARPF Reviewed; 54 AA.
AC P52265;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 25-MAY-2022, entry version 75.
DE RecName: Full=Ovomucoid;
DE Flags: Fragment;
OS Caracara plancus (Southern caracara) (Polyborus plancus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Falconiformes; Falconidae; Caracara.
OX NCBI_TaxID=8951;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=2073323; DOI=10.1007/bf01024766;
RA Laskowski M. Jr., Apostol I., Ardelt W., Cook J., Giletto A., Kelly C.A.,
RA Lu W., Park S.J., Qasim M.A., Whatley H.E., Wieczorek A., Wynn R.;
RT "Amino acid sequences of ovomucoid third domain from 25 additional species
RT of birds.";
RL J. Protein Chem. 9:715-725(1990).
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- DOMAIN: Avian ovomucoid consists of three homologous, tandem Kazal
CC family inhibitory domains.
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DR PIR; H61492; H61492.
DR AlphaFoldDB; P52265; -.
DR SMR; P52265; -.
DR iPTMnet; P52265; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR InterPro; IPR001239; Prot_inh_Kazal-m.
DR Pfam; PF00050; Kazal_1; 1.
DR PRINTS; PR00290; KAZALINHBTR.
DR SMART; SM00280; KAZAL; 1.
DR SUPFAM; SSF100895; SSF100895; 1.
DR PROSITE; PS00282; KAZAL_1; 1.
DR PROSITE; PS51465; KAZAL_2; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Disulfide bond; Glycoprotein;
KW Protease inhibitor; Repeat; Secreted; Serine protease inhibitor.
FT CHAIN <1..>54
FT /note="Ovomucoid"
FT /id="PRO_0000073168"
FT DOMAIN 4..54
FT /note="Kazal-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00798"
FT SITE 16..17
FT /note="Reactive bond 3"
FT CARBOHYD 43
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000269|PubMed:2073323"
FT DISULFID 6..36
FT DISULFID 14..33
FT DISULFID 22..54
FT NON_TER 1
FT NON_TER 54
SQ SEQUENCE 54 AA; 5830 MW; 471F2E9547F423CD CRC64;
VATVDCSEYP KPVCSLEYMP LCGSDSQTYS NECNFCNAVV DSNGTLTLSH FGKC