ID   IOVO_DACNO              Reviewed;          55 AA.
AC   P05617;
DT   01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1988, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Ovomucoid;
DE   Flags: Fragment;
OS   Dacelo novaeguineae (Laughing kookaburra) (Dacelo gigas).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Coraciiformes; Alcedinidae; Dacelo.
OX   NCBI_TaxID=8939;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=3828298; DOI=10.1021/bi00375a028;
RA   Laskowski M. Jr., Kato I., Ardelt W., Cook J., Denton A., Empie M.W.,
RA   Kohr W.J., Park S.J., Parks K., Schatzley B.L., Schoenberger O.L.,
RA   Tashiro M., Vichot G., Whatley H.E., Wieczorek A., Wieczorek M.;
RT   "Ovomucoid third domains from 100 avian species: isolation, sequences, and
RT   hypervariability of enzyme-inhibitor contact residues.";
RL   Biochemistry 26:202-221(1987).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- DOMAIN: Avian ovomucoid consists of three homologous, tandem Kazal
CC       family inhibitory domains.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; I31442; I31442.
DR   AlphaFoldDB; P05617; -.
DR   SMR; P05617; -.
DR   iPTMnet; P05617; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   InterPro; IPR002350; Kazal_dom.
DR   InterPro; IPR036058; Kazal_dom_sf.
DR   InterPro; IPR001239; Prot_inh_Kazal-m.
DR   Pfam; PF00050; Kazal_1; 1.
DR   PRINTS; PR00290; KAZALINHBTR.
DR   SMART; SM00280; KAZAL; 1.
DR   SUPFAM; SSF100895; SSF100895; 1.
DR   PROSITE; PS00282; KAZAL_1; 1.
DR   PROSITE; PS51465; KAZAL_2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Glycoprotein;
KW   Protease inhibitor; Repeat; Secreted; Serine protease inhibitor.
FT   CHAIN           <1..>55
FT                   /note="Ovomucoid"
FT                   /id="PRO_0000073099"
FT   DOMAIN          5..55
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00798"
FT   SITE            17..18
FT                   /note="Reactive bond 3"
FT   CARBOHYD        44
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000269|PubMed:3828298"
FT   DISULFID        7..37
FT   DISULFID        15..34
FT   DISULFID        23..55
FT   NON_TER         1
FT   NON_TER         55
SQ   SEQUENCE   55 AA;  5975 MW;  A3FEA961DF12B42A CRC64;
     IATQVDCSEH PKPACTLDYR PICGSDSKTY SNKCDFCNAV MDSNGTLTLS HFGKC