IOVO_FRAFR
ID IOVO_FRAFR Reviewed; 53 AA.
AC P05597;
DT 01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1988, sequence version 1.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=Ovomucoid;
DE Flags: Fragment;
OS Francolinus francolinus (Black francolin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Perdicinae; Francolinus.
OX NCBI_TaxID=9023;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=3828298; DOI=10.1021/bi00375a028;
RA Laskowski M. Jr., Kato I., Ardelt W., Cook J., Denton A., Empie M.W.,
RA Kohr W.J., Park S.J., Parks K., Schatzley B.L., Schoenberger O.L.,
RA Tashiro M., Vichot G., Whatley H.E., Wieczorek A., Wieczorek M.;
RT "Ovomucoid third domains from 100 avian species: isolation, sequences, and
RT hypervariability of enzyme-inhibitor contact residues.";
RL Biochemistry 26:202-221(1987).
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- DOMAIN: Avian ovomucoid consists of three homologous, tandem Kazal
CC family inhibitory domains.
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DR PIR; G31436; G31436.
DR AlphaFoldDB; P05597; -.
DR SMR; P05597; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR Pfam; PF00050; Kazal_1; 1.
DR SMART; SM00280; KAZAL; 1.
DR SUPFAM; SSF100895; SSF100895; 1.
DR PROSITE; PS00282; KAZAL_1; 1.
DR PROSITE; PS51465; KAZAL_2; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Disulfide bond; Glycoprotein;
KW Protease inhibitor; Repeat; Secreted; Serine protease inhibitor.
FT CHAIN <1..>53
FT /note="Ovomucoid"
FT /id="PRO_0000073111"
FT DOMAIN 3..53
FT /note="Kazal-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00798"
FT SITE 15..16
FT /note="Reactive bond 3"
FT CARBOHYD 42
FT /note="N-linked (GlcNAc...) asparagine"
FT DISULFID 5..35
FT DISULFID 13..32
FT DISULFID 21..53
FT NON_TER 1
FT NON_TER 53
SQ SEQUENCE 53 AA; 5788 MW; 60A553038FEAC350 CRC64;
VSVDCSGYPK PECTAEETPL CGSDNKTYRN KCNFCNAVVE SNGTLTLRHF GKC