ID   IOVO_MELOE              Reviewed;          56 AA.
AC   P68436; P01004;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Ovomucoid;
DE   Flags: Fragment;
OS   Meleagris ocellata (Ocellated turkey) (Agriocharis ocellata).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Meleagridinae; Meleagris.
OX   NCBI_TaxID=9101;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=3828298; DOI=10.1021/bi00375a028;
RA   Laskowski M. Jr., Kato I., Ardelt W., Cook J., Denton A., Empie M.W.,
RA   Kohr W.J., Park S.J., Parks K., Schatzley B.L., Schoenberger O.L.,
RA   Tashiro M., Vichot G., Whatley H.E., Wieczorek A., Wieczorek M.;
RT   "Ovomucoid third domains from 100 avian species: isolation, sequences, and
RT   hypervariability of enzyme-inhibitor contact residues.";
RL   Biochemistry 26:202-221(1987).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- DOMAIN: Avian ovomucoid consists of three homologous, tandem Kazal
CC       family inhibitory domains.
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DR   PIR; C31444; C31444.
DR   PDB; 2NU0; X-ray; 1.95 A; I=6-56.
DR   PDB; 2NU1; X-ray; 1.80 A; I=6-56.
DR   PDB; 2NU2; X-ray; 1.65 A; I=6-56.
DR   PDB; 2NU3; X-ray; 1.80 A; I=6-56.
DR   PDB; 2NU4; X-ray; 1.75 A; I=6-56.
DR   PDBsum; 2NU0; -.
DR   PDBsum; 2NU1; -.
DR   PDBsum; 2NU2; -.
DR   PDBsum; 2NU3; -.
DR   PDBsum; 2NU4; -.
DR   AlphaFoldDB; P68436; -.
DR   SMR; P68436; -.
DR   EvolutionaryTrace; P68436; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   InterPro; IPR002350; Kazal_dom.
DR   InterPro; IPR036058; Kazal_dom_sf.
DR   InterPro; IPR001239; Prot_inh_Kazal-m.
DR   Pfam; PF00050; Kazal_1; 1.
DR   PRINTS; PR00290; KAZALINHBTR.
DR   SMART; SM00280; KAZAL; 1.
DR   SUPFAM; SSF100895; SSF100895; 1.
DR   PROSITE; PS00282; KAZAL_1; 1.
DR   PROSITE; PS51465; KAZAL_2; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Direct protein sequencing; Disulfide bond; Glycoprotein;
KW   Protease inhibitor; Repeat; Secreted; Serine protease inhibitor.
FT   CHAIN           <1..>56
FT                   /note="Ovomucoid"
FT                   /id="PRO_0000073049"
FT   DOMAIN          6..56
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00798"
FT   SITE            18..19
FT                   /note="Reactive bond 3"
FT   CARBOHYD        45
FT                   /note="N-linked (GlcNAc...) asparagine"
FT   DISULFID        8..38
FT   DISULFID        16..35
FT   DISULFID        24..56
FT   NON_TER         1
FT   NON_TER         56
FT   STRAND          23..25
FT                   /evidence="ECO:0007829|PDB:2NU1"
FT   STRAND          30..33
FT                   /evidence="ECO:0007829|PDB:2NU1"
FT   HELIX           34..43
FT                   /evidence="ECO:0007829|PDB:2NU1"
FT   TURN            44..46
FT                   /evidence="ECO:0007829|PDB:2NU1"
FT   STRAND          50..54
FT                   /evidence="ECO:0007829|PDB:2NU1"
SQ   SEQUENCE   56 AA;  6021 MW;  C6C0BE5E3081CFE5 CRC64;
     LAAVSVDCSE YPKPACTLEY RPLCGSDNKT YGNKCNFCNA VVESNGTLTL SHFGKC