IOVO_ORTVE
ID IOVO_ORTVE Reviewed; 56 AA.
AC P05582;
DT 01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1988, sequence version 1.
DT 25-MAY-2022, entry version 86.
DE RecName: Full=Ovomucoid;
DE Flags: Fragment;
OS Ortalis vetula (Plain chachalaca) (Penelope vetula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Cracidae;
OC Ortalis.
OX NCBI_TaxID=8984;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=3828298; DOI=10.1021/bi00375a028;
RA Laskowski M. Jr., Kato I., Ardelt W., Cook J., Denton A., Empie M.W.,
RA Kohr W.J., Park S.J., Parks K., Schatzley B.L., Schoenberger O.L.,
RA Tashiro M., Vichot G., Whatley H.E., Wieczorek A., Wieczorek M.;
RT "Ovomucoid third domains from 100 avian species: isolation, sequences, and
RT hypervariability of enzyme-inhibitor contact residues.";
RL Biochemistry 26:202-221(1987).
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- DOMAIN: Avian ovomucoid consists of three homologous, tandem Kazal
CC family inhibitory domains.
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DR PIR; B31438; B31438.
DR AlphaFoldDB; P05582; -.
DR SMR; P05582; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR Pfam; PF00050; Kazal_1; 1.
DR SMART; SM00280; KAZAL; 1.
DR SUPFAM; SSF100895; SSF100895; 1.
DR PROSITE; PS00282; KAZAL_1; 1.
DR PROSITE; PS51465; KAZAL_2; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Disulfide bond; Glycoprotein;
KW Protease inhibitor; Repeat; Secreted; Serine protease inhibitor.
FT CHAIN <1..>56
FT /note="Ovomucoid"
FT /id="PRO_0000073153"
FT DOMAIN 6..56
FT /note="Kazal-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00798"
FT SITE 18..19
FT /note="Reactive bond 3"
FT CARBOHYD 45
FT /note="N-linked (GlcNAc...) asparagine"
FT DISULFID 8..38
FT DISULFID 16..35
FT DISULFID 24..56
FT NON_TER 1
FT NON_TER 56
SQ SEQUENCE 56 AA; 6049 MW; 583A08269CB4D989 CRC64;
FAPVNVDCSD HPKPACLQEQ KPICGSDNKT YDNKCSFCNA VVDSNGTLTL SHFGKC