ID   IOVO_SCYNO              Reviewed;          52 AA.
AC   P52253;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Ovomucoid;
DE   Flags: Fragment;
OS   Scythrops novaehollandiae (Channel-billed cuckoo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Scythrops.
OX   NCBI_TaxID=30394;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=8251062; DOI=10.1007/bf01025042;
RA   Apostol I., Giletto A., Komiyama T., Zhang W., Laskowski M. Jr.;
RT   "Amino acid sequences of ovomucoid third domains from 27 additional species
RT   of birds.";
RL   J. Protein Chem. 12:419-433(1993).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- DOMAIN: Avian ovomucoid consists of three homologous, tandem Kazal
CC       family inhibitory domains.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; B61589; B61589.
DR   AlphaFoldDB; P52253; -.
DR   SMR; P52253; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   InterPro; IPR002350; Kazal_dom.
DR   InterPro; IPR036058; Kazal_dom_sf.
DR   Pfam; PF00050; Kazal_1; 1.
DR   SMART; SM00280; KAZAL; 1.
DR   SUPFAM; SSF100895; SSF100895; 1.
DR   PROSITE; PS00282; KAZAL_1; 1.
DR   PROSITE; PS51465; KAZAL_2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Glycoprotein;
KW   Protease inhibitor; Repeat; Secreted; Serine protease inhibitor.
FT   CHAIN           <1..>52
FT                   /note="Ovomucoid"
FT                   /id="PRO_0000073177"
FT   DOMAIN          2..52
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00798"
FT   SITE            14..15
FT                   /note="Reactive bond 3"
FT   CARBOHYD        41
FT                   /note="N-linked (GlcNAc...) asparagine"
FT   DISULFID        4..34
FT   DISULFID        12..31
FT   DISULFID        20..52
FT   NON_TER         1
FT   NON_TER         52
SQ   SEQUENCE   52 AA;  5621 MW;  16BF618E9BC3BC1E CRC64;
     TVDCSDYPKP VCTLEEMPLC GSDNKTYGNK CNFCNAVVDS NGTLTLSHFG KC