ID   IP23_CAPAN              Reviewed;          52 AA.
AC   P83241;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Proteinase inhibitor PSI-1.2;
OS   Capsicum annuum (Capsicum pepper).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum.
OX   NCBI_TaxID=4072 {ECO:0000305};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, MASS SPECTROMETRY, AND DISULFIDE BONDS.
RC   TISSUE=Seed;
RX   PubMed=11604534; DOI=10.1110/ps.21701;
RA   Antcheva N., Pintar A., Patthy A., Simoncsits A., Barta E., Tchorbanov B.,
RA   Pongor S.;
RT   "Proteins of circularly permuted sequence present within the same organism:
RT   the major serine proteinase inhibitor from Capsicum annuum seeds.";
RL   Protein Sci. 10:2280-2290(2001).
CC   -!- FUNCTION: Potent inhibitor of trypsin and a weaker inhibitor of
CC       chymotrypsin. It does not inhibit elastase and subtilisin DY.
CC       {ECO:0000269|PubMed:11604534}.
CC   -!- MASS SPECTROMETRY: Mass=5594.2; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:11604534};
CC   -!- SIMILARITY: Belongs to the protease inhibitor I20 (potato type II
CC       proteinase inhibitor) family. {ECO:0000305}.
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DR   AlphaFoldDB; P83241; -.
DR   SMR; P83241; -.
DR   MEROPS; I20.952; -.
DR   Proteomes; UP000189700; Genome assembly.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:UniProtKB.
DR   InterPro; IPR003465; Prot_inh_I20.
DR   Pfam; PF02428; Prot_inhib_II; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Protease inhibitor;
KW   Serine protease inhibitor.
FT   CHAIN           1..52
FT                   /note="Proteinase inhibitor PSI-1.2"
FT                   /id="PRO_0000217672"
FT   DISULFID        3..32
FT                   /evidence="ECO:0000269|PubMed:11604534"
FT   DISULFID        7..28
FT                   /evidence="ECO:0000269|PubMed:11604534"
FT   DISULFID        16..38
FT                   /evidence="ECO:0000269|PubMed:11604534"
FT   DISULFID        31..49
FT                   /evidence="ECO:0000269|PubMed:11604534"
SQ   SEQUENCE   52 AA;  5604 MW;  201823D8DA49CC61 CRC64;
     KACPRNCDTD IAYMVCPSSG ERIIRKVCTN CCAAQKGCKL FRSNGSIKCT GT