IPGC_SHIDY
ID IPGC_SHIDY Reviewed; 155 AA.
AC P0A2U5; P18008;
DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 59.
DE RecName: Full=Chaperone protein IpgC;
GN Name=ipgC; Synonyms=ippI;
OS Shigella dysenteriae.
OG Plasmid Invasion.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=622;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=CG097;
RX PubMed=1766387; DOI=10.1111/j.1365-2958.1991.tb02151.x;
RA Yao R., Palchaudhuri S.;
RT "Nucleotide sequence of the ipaBCD structural genes of Shigella
RT dysenteriae.";
RL Mol. Microbiol. 5:2217-2221(1991).
CC -!- FUNCTION: Assists the correct folding of nascent IpaB. Once it is bound
CC to IpaB, it binds to IpaC and impedes their premature association that
CC would lead to their degradation in the absence of IpcG (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LcrH/SycD chaperone family. {ECO:0000305}.
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DR EMBL; X60777; CAA43189.1; -; Genomic_DNA.
DR PIR; S15576; S15576.
DR RefSeq; WP_000055835.1; NZ_UAUQ01000015.1.
DR AlphaFoldDB; P0A2U5; -.
DR SMR; P0A2U5; -.
DR OMA; NEPRFPF; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR005415; T3SS_Ca_resp_chp_LcrH/SycD.
DR InterPro; IPR016379; T3SS_Ca_resp_chp_LcrH/SycD_sub.
DR InterPro; IPR011716; TPR-3.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF07720; TPR_3; 2.
DR PIRSF; PIRSF003165; Chaperone_SicA; 1.
DR PRINTS; PR01595; SYCDCHAPRONE.
DR SUPFAM; SSF48452; SSF48452; 1.
DR TIGRFAMs; TIGR02552; LcrH_SycD; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Plasmid; Virulence.
FT CHAIN 1..155
FT /note="Chaperone protein IpgC"
FT /id="PRO_0000206483"
SQ SEQUENCE 155 AA; 17756 MW; F46E39A92B8ADEC7 CRC64;
MSLNITENES ISTAVIDAIN SGATLKDINA IPDDMMDDIY SYAYDFYNKG RIEEAEVFFR
FLCIYDFYNV DYIMGLAAIY QIKEQFQQAA DLYAVAFALG KNDYTPVFHT GQCQLRLKAP
LKAKECFELV IQHSNDEKLK IKAQSYLDAI QDIKE