ID   IPI1_ASPOR              Reviewed;         369 AA.
AC   Q2UU13;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Pre-rRNA-processing protein ipi1;
GN   Name=ipi1; ORFNames=AO090009000506;
OS   Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=510516;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42149 / RIB 40;
RX   PubMed=16372010; DOI=10.1038/nature04300;
RA   Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA   Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA   Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA   Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA   Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA   Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA   Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA   Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA   Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA   Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA   Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA   Kikuchi H.;
RT   "Genome sequencing and analysis of Aspergillus oryzae.";
RL   Nature 438:1157-1161(2005).
CC   -!- FUNCTION: Component of the RIX1 complex required for processing of ITS2
CC       sequences from 35S pre-rRNA. {ECO:0000250|UniProtKB:P38803}.
CC   -!- SUBUNIT: Component of the RIX1 complex, composed of ipi1, rix1/ipi2 and
CC       ipi3 in a 1:2:2 stoichiometry. The complex interacts (via rix1) with
CC       mdn1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome
CC       particles. {ECO:0000250|UniProtKB:P38803}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P38803}.
CC   -!- SIMILARITY: Belongs to the IPI1/TEX10 family. {ECO:0000305}.
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DR   EMBL; AP007150; BAE54952.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2UU13; -.
DR   SMR; Q2UU13; -.
DR   STRING; 510516.Q2UU13; -.
DR   EnsemblFungi; BAE54952; BAE54952; AO090009000506.
DR   VEuPathDB; FungiDB:AO090009000506; -.
DR   HOGENOM; CLU_050252_2_0_1; -.
DR   OMA; CAGGWVK; -.
DR   Proteomes; UP000006564; Chromosome 1.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR024679; Ipi1_N.
DR   InterPro; IPR037947; TEX10/Ipi1.
DR   PANTHER; PTHR16056:SF2; PTHR16056:SF2; 1.
DR   Pfam; PF12333; Ipi1_N; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..369
FT                   /note="Pre-rRNA-processing protein ipi1"
FT                   /id="PRO_0000308715"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          349..369
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   369 AA;  40090 MW;  6C45EB28145DD50D CRC64;
     MGSSAKKKKE KQKDFTKAKL KVGKAKGKPE NFTDTSFKSK GIVLNQQSLT LNAPTSNTQF
     THHVSLLSSK SDSQRRDSLA HLTTSISSRP VNSPLPQPVS VILPTLLPLI LDANTGVRTQ
     LLKLFRALPQ SDIRDHVPQL LPYIRAGMTH LAADIRVSAV EVLSWLIDVA GTEVVSSAGG
     WIKTLNCFLS VLGWHTEESA KWSANRASFG KSGAKGQPMM KVLTVLAEFL NAGIGAPANE
     AQDVDMLGSG GVAGWEFPLC QTAVHMVPDT AAPYAYLNLF GQPRDEEGEM YETWEDRYRV
     FSNRFLRAIQ RGLENARQEG GEMGRASSGA SKVLKEAVAY GTGIADRDIV SSHDSTSRGT
     SIHDLEPKE