IPI1_MAGO7
ID IPI1_MAGO7 Reviewed; 345 AA.
AC A4RBW8; G4NJ32; Q2KG27;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 1.
DT 25-MAY-2022, entry version 76.
DE RecName: Full=Pre-rRNA-processing protein IPI1;
GN Name=IPI1; ORFNames=MGCH7_ch7g508, MGG_02761;
OS Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS fungus) (Pyricularia oryzae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX NCBI_TaxID=242507;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RA Thon M.R., Pan H., Diener A., Papalas J., Taro A., Mitchell T.K.,
RA Dean R.A.;
RT "The sequence of Magnaporthe grisea chromosome 7.";
RL Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX PubMed=15846337; DOI=10.1038/nature03449;
RA Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL Nature 434:980-986(2005).
CC -!- FUNCTION: Component of the RIX1 complex required for processing of ITS2
CC sequences from 35S pre-rRNA. {ECO:0000250|UniProtKB:P38803}.
CC -!- SUBUNIT: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and
CC IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with
CC MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome
CC particles. {ECO:0000250|UniProtKB:P38803}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P38803}.
CC -!- SIMILARITY: Belongs to the IPI1/TEX10 family. {ECO:0000305}.
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DR EMBL; CM000230; EAQ71101.1; -; Genomic_DNA.
DR EMBL; CM001237; EHA46248.1; -; Genomic_DNA.
DR RefSeq; XP_003720991.1; XM_003720943.1.
DR AlphaFoldDB; A4RBW8; -.
DR SMR; A4RBW8; -.
DR STRING; 318829.MGG_02761T0; -.
DR EnsemblFungi; MGG_02761T0; MGG_02761T0; MGG_02761.
DR GeneID; 2682766; -.
DR KEGG; mgr:MGG_02761; -.
DR VEuPathDB; FungiDB:MGG_02761; -.
DR eggNOG; KOG2149; Eukaryota.
DR HOGENOM; CLU_050252_2_0_1; -.
DR InParanoid; A4RBW8; -.
DR OMA; CAGGWVK; -.
DR OrthoDB; 1145058at2759; -.
DR Proteomes; UP000009058; Chromosome 7.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; -; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024679; Ipi1_N.
DR InterPro; IPR037947; TEX10/Ipi1.
DR PANTHER; PTHR16056:SF2; PTHR16056:SF2; 1.
DR Pfam; PF12333; Ipi1_N; 1.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..345
FT /note="Pre-rRNA-processing protein IPI1"
FT /id="PRO_0000308723"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 345 AA; 37533 MW; 736CF17817B5F1CE CRC64;
MGSSVRKKKE KKKDFQKTKL KVGKAKEKPA SFTDTSFKSR AIVVAQSSLT VEGPNPVEQF
KHYLSLASTS RSENQRRDAL AFLTTQLSHQ PPNNPVGTPA ILAKLLPLIS DSNSGVRTQL
YKLLQAFPSA DIQPQVERIS MYVRAGMTHL SADIRDDTLS IMEWLLEVAG SEVVSCAGGW
MKTLNVFAAM LGWSSIVAAN AAAAAGSAPR NKGWTSAPKS TFGAAKGGAS YARQLLALAK
FLEIGFRPEA TGSGGQRTLW NSLYRLPRTS NPFGYLNLFG APRDEDSEIY ADREDRQRVF
SRKWHAVITK GLEEAKKEGG AVGRAGAVLN QTLKDGLADY DDHVL