ID   IPI1_SCLS1              Reviewed;         348 AA.
AC   A7EI93;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Pre-rRNA-processing protein ipi1;
GN   Name=ipi1; ORFNames=SS1G_05035;
OS   Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold)
OS   (Whetzelinia sclerotiorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Sclerotinia.
OX   NCBI_TaxID=665079;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 18683 / 1980 / Ss-1;
RX   PubMed=21876677; DOI=10.1371/journal.pgen.1002230;
RA   Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A.,
RA   Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA   Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.-M.,
RA   Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA   Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA   Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA   Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA   Grossetete S., Gueldener U., Henrissat B., Howlett B.J., Kodira C.,
RA   Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA   Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA   Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA   Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA   Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M.;
RT   "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT   sclerotiorum and Botrytis cinerea.";
RL   PLoS Genet. 7:E1002230-E1002230(2011).
CC   -!- FUNCTION: Component of the RIX1 complex required for processing of ITS2
CC       sequences from 35S pre-rRNA. {ECO:0000250|UniProtKB:P38803}.
CC   -!- SUBUNIT: Component of the RIX1 complex, composed of ipi1, rix1/ipi2 and
CC       ipi3 in a 1:2:2 stoichiometry. The complex interacts (via rix1) with
CC       mdn1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome
CC       particles. {ECO:0000250|UniProtKB:P38803}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P38803}.
CC   -!- SIMILARITY: Belongs to the IPI1/TEX10 family. {ECO:0000305}.
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DR   EMBL; CH476626; EDO02559.1; -; Genomic_DNA.
DR   RefSeq; XP_001593608.1; XM_001593558.1.
DR   AlphaFoldDB; A7EI93; -.
DR   SMR; A7EI93; -.
DR   STRING; 665079.A7EI93; -.
DR   EnsemblFungi; EDO02559; EDO02559; SS1G_05035.
DR   GeneID; 5490273; -.
DR   KEGG; ssl:SS1G_05035; -.
DR   VEuPathDB; FungiDB:sscle_08g063610; -.
DR   eggNOG; KOG2149; Eukaryota.
DR   HOGENOM; CLU_050252_2_0_1; -.
DR   InParanoid; A7EI93; -.
DR   OMA; CAGGWVK; -.
DR   Proteomes; UP000001312; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0097344; C:Rix1 complex; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR024679; Ipi1_N.
DR   InterPro; IPR037947; TEX10/Ipi1.
DR   PANTHER; PTHR16056:SF2; PTHR16056:SF2; 1.
DR   Pfam; PF12333; Ipi1_N; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..348
FT                   /note="Pre-rRNA-processing protein ipi1"
FT                   /id="PRO_0000308730"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   348 AA;  38249 MW;  183681BD8FD0B0BD CRC64;
     MGSSARKKKE KKKDFQKTKL RVGKTKAKAD NFTDTSFKSK SIVVNQQSLT TSAPSNVVQF
     THYLSLASSS KSDTQRKDAL SFLTTQLSSQ PVNEAIPLPT AVILPKLLPL ILDGNASVRS
     QLLKFLRLLP PADIGDRVES ALLYTRAGMT HLATEIRVDA LAVLEWLLQV AGDDVVSCPG
     GWVKTLKSFM SMIGWTTSSA TSKWSSASRV SFGISRASFE KSGKTLPRQL LVLSQFLKAG
     LVEPDTAAQP TTSDNHFPLF DVERHMIPSR ANAYAHLNLF GSSRDEEGEM YIDREDRQRV
     FHKRFQADVV TGVEHAKREA GEAGRAAAVL TKVLRDGMND YSGVDDTQ