ID   IPIL1_RAT               Reviewed;         547 AA.
AC   Q66H52;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1;
DE   Flags: Precursor;
GN   Name=Itpripl1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ITPRIP family. {ECO:0000305}.
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DR   EMBL; BC082013; AAH82013.1; -; mRNA.
DR   RefSeq; NP_001020214.1; NM_001025043.1.
DR   AlphaFoldDB; Q66H52; -.
DR   STRING; 10116.ENSRNOP00000016172; -.
DR   PaxDb; Q66H52; -.
DR   Ensembl; ENSRNOT00000110996; ENSRNOP00000079259; ENSRNOG00000012151.
DR   Ensembl; ENSRNOT00000113642; ENSRNOP00000077758; ENSRNOG00000012151.
DR   GeneID; 499885; -.
DR   KEGG; rno:499885; -.
DR   UCSC; RGD:1564158; rat.
DR   CTD; 150771; -.
DR   RGD; 1564158; Itpripl1.
DR   eggNOG; ENOG502RX8U; Eukaryota.
DR   GeneTree; ENSGT01050000244827; -.
DR   HOGENOM; CLU_025485_2_0_1; -.
DR   InParanoid; Q66H52; -.
DR   OMA; HLQLEDC; -.
DR   OrthoDB; 1434451at2759; -.
DR   PhylomeDB; Q66H52; -.
DR   TreeFam; TF332277; -.
DR   PRO; PR:Q66H52; -.
DR   Proteomes; UP000002494; Chromosome 3.
DR   Bgee; ENSRNOG00000012151; Expressed in testis and 18 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   InterPro; IPR024808; IP3R-int-like_1.
DR   InterPro; IPR026250; ITPRIP_fam.
DR   InterPro; IPR024810; Mab-21_dom.
DR   PANTHER; PTHR10656:SF40; PTHR10656:SF40; 1.
DR   Pfam; PF03281; Mab-21; 1.
DR   PRINTS; PR02107; INOS145TPRIP.
DR   SMART; SM01265; Mab-21; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   CHAIN           17..547
FT                   /note="Inositol 1,4,5-trisphosphate receptor-interacting
FT                   protein-like 1"
FT                   /id="PRO_0000320568"
FT   TOPO_DOM        17..96
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        118..547
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   COILED          28..66
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   547 AA;  62548 MW;  2AF8D1ACA9F3228E CRC64;
     MAVISLLFLA VMYVVHHPLM VSDRMDLDTL ARSRQLEKRM SEEMRQLEIE FEERSRAAEE
     KQKAENFWRG DTSNDQLVLG KKDMRWPFQA SGQDGGPLGW MLGNLWNAGL FCLFLIFELL
     RQNMQHEPAF ESSSEEEEEE IRVVPVSSYT WLSGFPSQEA LESFYKHYIQ NAIRDLPCTC
     EFVESFVDDL IEACRVLSRR EAHPQLEDCL GIGAAFEKWG TLHETQKFDV LVPIVPPQGT
     MFILEMRDPT LGRRCGCVKV DSECVCKNEK LLGDVLCLVH HRDHSAMLSK CTSSIKAALC
     TSSHLDVYKT VQWFRNMVSN AWALVAHKYD FKLTLPPSTT TCKLRLDYRS GRSLSISLVL
     GVQREDTLVY LVSQAPEREQ FTSVDWPESF AACEHLFLKL VGRFAPDNTC HLKCLQIILS
     LQDHQTLPPG ASRPILTSYH FKTALMHLLL RLPLTDWQHR MLSQRLQDLL WFLGRSLQQR
     SLHHFLIGNT HLPLTIPIPK AFRNAEPVNL FQHLVLNPVA HSQAVEEFHN LLAQVKTLPC
     SPLAGGL