ID   IPR_SOLME               Reviewed;          52 AA.
AC   P01078;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-1998, sequence version 2.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Proteinase inhibitor;
OS   Solanum melongena (Eggplant) (Aubergine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=4111;
RN   [1]
RP   PROTEIN SEQUENCE, AND PYROGLUTAMATE FORMATION AT GLN-1.
RX   PubMed=477995; DOI=10.1016/0014-5793(79)80843-1;
RA   Richardson M.;
RT   "The complete amino acid sequence and the trypsin reactive (inhibitory)
RT   site of the major proteinase inhibitor from the fruits of aubergine
RT   (Solanum melongena L.).";
RL   FEBS Lett. 104:322-326(1979).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the protease inhibitor I20 (potato type II
CC       proteinase inhibitor) family. {ECO:0000305}.
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DR   PIR; A01317; TIEO1.
DR   AlphaFoldDB; P01078; -.
DR   SMR; P01078; -.
DR   MEROPS; I20.952; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   InterPro; IPR003465; Prot_inh_I20.
DR   Pfam; PF02428; Prot_inhib_II; 2.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Protease inhibitor;
KW   Pyrrolidone carboxylic acid; Secreted; Serine protease inhibitor.
FT   CHAIN           1..52
FT                   /note="Proteinase inhibitor"
FT                   /id="PRO_0000217673"
FT   SITE            38..39
FT                   /note="Reactive bond for trypsin"
FT   MOD_RES         1
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:477995"
FT   DISULFID        3..40
FT                   /evidence="ECO:0000250"
FT   DISULFID        6..24
FT                   /evidence="ECO:0000250"
FT   DISULFID        7..36
FT                   /evidence="ECO:0000250"
FT   DISULFID        13..49
FT                   /evidence="ECO:0000250"
FT   VARIANT         2
FT                   /note="I -> L"
FT   VARIANT         6
FT                   /note="C -> N"
SQ   SEQUENCE   52 AA;  5579 MW;  C5B8C2F1D97B9217 CRC64;
     QICTNCCAGR KGCSYFSEDG TFICKGESNP ENPKACPRNC DGRIAYGICP LS