ID   IQCC_MOUSE              Reviewed;         418 AA.
AC   A2ADZ8; Q8K0F9; Q8R0F4;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=IQ domain-containing protein C;
GN   Name=Iqcc;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 64-418.
RC   STRAIN=FVB/N; TISSUE=Eye, and Mammary tumor;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; AL671759; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC026978; AAH26978.1; -; mRNA.
DR   EMBL; BC031493; -; NOT_ANNOTATED_CDS; mRNA.
DR   CCDS; CCDS38886.1; -.
DR   RefSeq; NP_932143.2; NM_198026.2.
DR   AlphaFoldDB; A2ADZ8; -.
DR   SMR; A2ADZ8; -.
DR   STRING; 10090.ENSMUSP00000040584; -.
DR   iPTMnet; A2ADZ8; -.
DR   PhosphoSitePlus; A2ADZ8; -.
DR   PaxDb; A2ADZ8; -.
DR   PRIDE; A2ADZ8; -.
DR   ProteomicsDB; 269086; -.
DR   Antibodypedia; 31251; 105 antibodies from 16 providers.
DR   Ensembl; ENSMUST00000046675; ENSMUSP00000040584; ENSMUSG00000040795.
DR   GeneID; 230767; -.
DR   KEGG; mmu:230767; -.
DR   UCSC; uc008uxs.1; mouse.
DR   CTD; 55721; -.
DR   MGI; MGI:2446212; Iqcc.
DR   VEuPathDB; HostDB:ENSMUSG00000040795; -.
DR   eggNOG; ENOG502S8YC; Eukaryota.
DR   GeneTree; ENSGT00390000017195; -.
DR   HOGENOM; CLU_046548_0_0_1; -.
DR   InParanoid; A2ADZ8; -.
DR   OMA; FPCKEPE; -.
DR   OrthoDB; 868750at2759; -.
DR   PhylomeDB; A2ADZ8; -.
DR   TreeFam; TF330928; -.
DR   BioGRID-ORCS; 230767; 1 hit in 73 CRISPR screens.
DR   ChiTaRS; Iqcc; mouse.
DR   PRO; PR:A2ADZ8; -.
DR   Proteomes; UP000000589; Chromosome 4.
DR   RNAct; A2ADZ8; protein.
DR   Bgee; ENSMUSG00000040795; Expressed in spermatocyte and 74 other tissues.
DR   ExpressionAtlas; A2ADZ8; baseline and differential.
DR   Genevisible; A2ADZ8; MM.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR042506; IQCC.
DR   PANTHER; PTHR16049; PTHR16049; 1.
DR   PROSITE; PS50096; IQ; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..418
FT                   /note="IQ domain-containing protein C"
FT                   /id="PRO_0000282546"
FT   DOMAIN          6..35
FT                   /note="IQ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00116"
FT   REGION          101..142
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          230..264
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          280..299
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          327..355
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          376..418
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          141..176
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        125..142
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        230..245
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        388..407
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   418 AA;  46912 MW;  F6B7F52892E90F1D CRC64;
     MDPDLFLRKV STLQAGFRGF LVRRQFQSLR AEYEAIVQEI EGDLSTLQWT GGWIPKPVFL
     PEAKSHQSWK AEKISNPEQK LWSHSPHKDS EKELIWEEMV QKKTEKSPAN PGSLCRDDSA
     WPQAEQGRKA SQGNSQDTSV SKMENADLGL SQSQQELQEQ RNHLAMELLW LQQAINSRKE
     YLILKQTLRS PEASQTRDKH RGQAYEKTSL HSSCVLDNQS YRDRIIGESH HAEDSSHKGR
     LKPQKHPDSV TSAGKTTAGS KGRELCYRNS ASQLPAALES QAGGDRVTKG PDHGGQPFKE
     TSLQQLKVLE DQIPGDLKFR SPCSRKAETQ LPTLSENQNI EDRYSRKPSR SAGPCDLNIL
     EGHMIWDETL AGQEQGSLDL IRTKPPKSQP PSAGSSGHGN TSELSPEGWK NRGILQWR