IQCF3_MOUSE
ID IQCF3_MOUSE Reviewed; 203 AA.
AC Q9D498;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=IQ domain-containing protein F3;
DE AltName: Full=Testis-specific IQ motif-containing protein 2;
GN Name=Iqcf3;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Testis;
RA Nie D.-S., Liu Y., Lu G.-X.;
RT "Mus musculus testis-specific IQ motif containing protein 2.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; DQ153247; AAZ78215.1; -; mRNA.
DR EMBL; AK016688; BAB30380.1; -; mRNA.
DR EMBL; AK132739; BAE21327.1; -; mRNA.
DR EMBL; BC049549; AAH49549.1; -; mRNA.
DR CCDS; CCDS40758.1; -.
DR RefSeq; NP_080921.2; NM_026645.3.
DR AlphaFoldDB; Q9D498; -.
DR SMR; Q9D498; -.
DR PaxDb; Q9D498; -.
DR PRIDE; Q9D498; -.
DR ProteomicsDB; 269502; -.
DR DNASU; 68265; -.
DR Ensembl; ENSMUST00000062917; ENSMUSP00000054276; ENSMUSG00000118396.
DR Ensembl; ENSMUST00010126032; ENSMUSP00001068197; ENSMUSG00001074846.
DR GeneID; 68265; -.
DR KEGG; mmu:68265; -.
DR UCSC; uc009rkg.1; mouse.
DR CTD; 401067; -.
DR MGI; MGI:1915515; Iqcf3.
DR VEuPathDB; HostDB:ENSMUSG00000118396; -.
DR GeneTree; ENSGT00390000004641; -.
DR InParanoid; Q9D498; -.
DR TreeFam; TF337908; -.
DR BioGRID-ORCS; 68265; 1 hit in 71 CRISPR screens.
DR ChiTaRS; Iqcf3; mouse.
DR PRO; PR:Q9D498; -.
DR Proteomes; UP000000589; Chromosome 9.
DR RNAct; Q9D498; protein.
DR Bgee; ENSMUSG00000118396; Expressed in seminiferous tubule of testis and 46 other tissues.
DR ExpressionAtlas; Q9D498; baseline and differential.
DR Genevisible; Q9D498; MM.
DR GO; GO:0001669; C:acrosomal vesicle; IBA:GO_Central.
DR GO; GO:0005516; F:calmodulin binding; IBA:GO_Central.
DR GO; GO:2000344; P:positive regulation of acrosome reaction; IBA:GO_Central.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR039887; IQCF.
DR PANTHER; PTHR21633; PTHR21633; 2.
DR Pfam; PF00612; IQ; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..203
FT /note="IQ domain-containing protein F3"
FT /id="PRO_0000339382"
FT DOMAIN 129..158
FT /note="IQ"
FT REGION 1..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..82
FT /evidence="ECO:0000255"
FT COMPBIAS 1..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..111
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 203 AA; 23500 MW; 5F2823CDAEDF6F1A CRC64;
MELDQDKKKE TPEETENVNE VQLEKQNQDE ETEAEAEEAD KAILERSDSV KTECPPQAEK
QNQDEETEAE AEEADKAILE RSDSVKTECP PQAEKQIQEE KCETQEADRS EGTELGKLHS
QLDQLPDNVM LAGVKIQAWW RGTLVRRTLL LAALNAWTIQ CWWREAKARL QGRKLHEVMR
YRLRNLNLKS ISKRKQPNQS SFL
