IQCF5_HUMAN
ID IQCF5_HUMAN Reviewed; 148 AA.
AC A8MTL0;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 2.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=IQ domain-containing protein F5;
GN Name=IQCF5;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG The Cancer Genome Anatomy Project (CGAP) at the National Cancer Institute;
RL Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16641997; DOI=10.1038/nature04728;
RA Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O.,
RA Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X.,
RA Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT "The DNA sequence, annotation and analysis of human chromosome 3.";
RL Nature 440:1194-1198(2006).
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DR EMBL; BF059325; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AC097636; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS46838.1; -.
DR RefSeq; NP_001138531.1; NM_001145059.1.
DR AlphaFoldDB; A8MTL0; -.
DR SMR; A8MTL0; -.
DR BioGRID; 132987; 2.
DR IntAct; A8MTL0; 2.
DR BioMuta; IQCF5; -.
DR MassIVE; A8MTL0; -.
DR PaxDb; A8MTL0; -.
DR PeptideAtlas; A8MTL0; -.
DR PRIDE; A8MTL0; -.
DR ProteomicsDB; 2032; -.
DR Antibodypedia; 63832; 16 antibodies from 2 providers.
DR DNASU; 389124; -.
DR Ensembl; ENST00000446461.2; ENSP00000394653.1; ENSG00000214681.4.
DR GeneID; 389124; -.
DR KEGG; hsa:389124; -.
DR MANE-Select; ENST00000446461.2; ENSP00000394653.1; NM_001145059.2; NP_001138531.1.
DR UCSC; uc011bdx.2; human.
DR CTD; 389124; -.
DR GeneCards; IQCF5; -.
DR HGNC; HGNC:35159; IQCF5.
DR HPA; ENSG00000214681; Tissue enriched (testis).
DR neXtProt; NX_A8MTL0; -.
DR OpenTargets; ENSG00000214681; -.
DR PharmGKB; PA164721062; -.
DR VEuPathDB; HostDB:ENSG00000214681; -.
DR eggNOG; ENOG502TCZD; Eukaryota.
DR GeneTree; ENSGT00390000004641; -.
DR HOGENOM; CLU_114989_0_0_1; -.
DR InParanoid; A8MTL0; -.
DR OMA; HSRGFIQ; -.
DR OrthoDB; 1354510at2759; -.
DR PhylomeDB; A8MTL0; -.
DR TreeFam; TF337908; -.
DR PathwayCommons; A8MTL0; -.
DR SignaLink; A8MTL0; -.
DR BioGRID-ORCS; 389124; 10 hits in 1059 CRISPR screens.
DR GenomeRNAi; 389124; -.
DR Pharos; A8MTL0; Tdark.
DR PRO; PR:A8MTL0; -.
DR Proteomes; UP000005640; Chromosome 3.
DR RNAct; A8MTL0; protein.
DR Bgee; ENSG00000214681; Expressed in sperm and 32 other tissues.
DR Genevisible; A8MTL0; HS.
DR GO; GO:0005516; F:calmodulin binding; IBA:GO_Central.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR039887; IQCF.
DR PANTHER; PTHR21633; PTHR21633; 1.
DR Pfam; PF00612; IQ; 2.
DR SMART; SM00015; IQ; 2.
DR PROSITE; PS50096; IQ; 2.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat.
FT CHAIN 1..148
FT /note="IQ domain-containing protein F5"
FT /id="PRO_0000345956"
FT DOMAIN 11..40
FT /note="IQ 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00116"
FT DOMAIN 67..96
FT /note="IQ 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00116"
FT CONFLICT 50
FT /note="E -> K (in Ref. 1; BF059325)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 148 AA; 18048 MW; EAA71C096FD2A9EB CRC64;
MGPEEKTIMT ERSAAVFIQA WWRGMLVRRT LLHAALRAWI IQCWWRQVLE KLLAKRRRMV
LEFYVQQEWA AVRLQSWVRM WCVRQRYCRL LNAVRIIQVY WRWHSCHSRV FIEGHYELKE
NQLNIQLEIS LGLQACKVQQ CIPLPLKE
