ID   IQCF6_HUMAN             Reviewed;         107 AA.
AC   A8MYZ5;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-FEB-2014, sequence version 3.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=IQ domain-containing protein F6;
GN   Name=IQCF6;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA   Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA   Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA   Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA   Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA   Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA   Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA   Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA   Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA   Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA   Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA   Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA   Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O.,
RA   Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X.,
RA   Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA   Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
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DR   EMBL; AC099050; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS54590.1; -.
DR   RefSeq; NP_001137305.2; NM_001143833.3.
DR   RefSeq; XP_011532030.1; XM_011533728.1.
DR   AlphaFoldDB; A8MYZ5; -.
DR   SMR; A8MYZ5; -.
DR   STRING; 9606.ENSP00000381760; -.
DR   GlyGen; A8MYZ5; 1 site, 1 O-linked glycan (1 site).
DR   iPTMnet; A8MYZ5; -.
DR   PhosphoSitePlus; A8MYZ5; -.
DR   BioMuta; IQCF6; -.
DR   MassIVE; A8MYZ5; -.
DR   PaxDb; A8MYZ5; -.
DR   PeptideAtlas; A8MYZ5; -.
DR   PRIDE; A8MYZ5; -.
DR   Antibodypedia; 71165; 25 antibodies from 10 providers.
DR   DNASU; 440956; -.
DR   Ensembl; ENST00000398780.5; ENSP00000381760.3; ENSG00000214686.7.
DR   GeneID; 440956; -.
DR   KEGG; hsa:440956; -.
DR   UCSC; uc021wyv.1; human.
DR   CTD; 440956; -.
DR   GeneCards; IQCF6; -.
DR   HGNC; HGNC:35158; IQCF6.
DR   HPA; ENSG00000214686; Tissue enriched (testis).
DR   neXtProt; NX_A8MYZ5; -.
DR   OpenTargets; ENSG00000214686; -.
DR   VEuPathDB; HostDB:ENSG00000214686; -.
DR   eggNOG; ENOG502TCZB; Eukaryota.
DR   GeneTree; ENSGT00390000004641; -.
DR   HOGENOM; CLU_114989_1_0_1; -.
DR   InParanoid; A8MYZ5; -.
DR   OrthoDB; 1354510at2759; -.
DR   PhylomeDB; A8MYZ5; -.
DR   TreeFam; TF337908; -.
DR   PathwayCommons; A8MYZ5; -.
DR   SignaLink; A8MYZ5; -.
DR   BioGRID-ORCS; 440956; 9 hits in 1011 CRISPR screens.
DR   GenomeRNAi; 440956; -.
DR   Pharos; A8MYZ5; Tdark.
DR   PRO; PR:A8MYZ5; -.
DR   Proteomes; UP000005640; Chromosome 3.
DR   RNAct; A8MYZ5; protein.
DR   Bgee; ENSG00000214686; Expressed in sperm and 34 other tissues.
DR   ExpressionAtlas; A8MYZ5; baseline and differential.
DR   Genevisible; A8MYZ5; HS.
DR   GO; GO:0005516; F:calmodulin binding; IBA:GO_Central.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR039887; IQCF.
DR   PANTHER; PTHR21633; PTHR21633; 1.
DR   Pfam; PF00612; IQ; 2.
DR   PROSITE; PS50096; IQ; 1.
PE   4: Predicted;
KW   Reference proteome; Repeat.
FT   CHAIN           1..107
FT                   /note="IQ domain-containing protein F6"
FT                   /id="PRO_0000343226"
FT   DOMAIN          42..71
FT                   /note="IQ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00116"
SQ   SEQUENCE   107 AA;  13059 MW;  4B822CE61AA52CDA CRC64;
     MVRRTLLQAA LRAWVIQCWW RSMQAKMLEQ RRRLALRLYT CQEWAVVKVQ AQVRMWQARR
     RFLQARQAAC IIQSHWRWHA SQTRGLIRGH YEVRASRLEL DIEILMT