ID   IQCH_DANRE              Reviewed;        1059 AA.
AC   Q1LXZ7;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=IQ motif-containing protein H;
GN   Name=iqch; ORFNames=si:dkey-246a16.2;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
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DR   EMBL; BX247951; CAK10802.1; -; Genomic_DNA.
DR   RefSeq; NP_001038594.1; NM_001045129.1.
DR   AlphaFoldDB; Q1LXZ7; -.
DR   STRING; 7955.ENSDARP00000074143; -.
DR   PaxDb; Q1LXZ7; -.
DR   Ensembl; ENSDART00000135049; ENSDARP00000115882; ENSDARG00000015476.
DR   GeneID; 567336; -.
DR   KEGG; dre:567336; -.
DR   CTD; 64799; -.
DR   ZFIN; ZDB-GENE-050419-242; iqch.
DR   eggNOG; ENOG502QSF3; Eukaryota.
DR   GeneTree; ENSGT00390000008908; -.
DR   HOGENOM; CLU_008013_0_0_1; -.
DR   InParanoid; Q1LXZ7; -.
DR   OrthoDB; 203701at2759; -.
DR   PhylomeDB; Q1LXZ7; -.
DR   PRO; PR:Q1LXZ7; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 18.
DR   Bgee; ENSDARG00000015476; Expressed in testis and 8 other tissues.
DR   ExpressionAtlas; Q1LXZ7; baseline and differential.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR038752; IQCH.
DR   PANTHER; PTHR14465; PTHR14465; 1.
DR   PROSITE; PS50096; IQ; 1.
PE   4: Predicted;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..1059
FT                   /note="IQ motif-containing protein H"
FT                   /id="PRO_0000282567"
FT   DOMAIN          401..430
FT                   /note="IQ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00116"
FT   REGION          245..267
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          6..35
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1059 AA;  118968 MW;  2723EC779A5FBD08 CRC64;
     MASVLKNKDE VGNILVKVQD DLRQLKKNIV QFTVQENGEI LDIQALDAAI IRTENGIRRH
     AEDYLKTINN QVLTLPSIEE PEKKTAHPKL VTWQPPYEAL PIAHPHRSPI PGPSPGEKHK
     TAFIMRLLHN PFHPRNKEIF QQNYGIQLPH LQKRTSIGIQ RVVTGSNLGN FAIAHLQPKP
     PPECQDAVAE LQPSAADLSS VQTPVQPKAV HVLQREDSGQ NESKKVYKQE MDVRRDGMAL
     RRSAMESAES RLLRAPPPSA ASASSDNRVL TRGLARLSPI NPQSLPVPAV VSKYPFTIVD
     GQIDPDAADF CRYKKQYCLY WGAMVEALER LQRMLLDFAV PLARVCGERL AACVQSGELN
     WRDGRGRCTH VEKLLSVLEN RDEVWDLMCQ PGQRYKGNGG HQAAAVRIQT CWRRYSARTA
     YLIRLRSKWA AEIIAMSLLK RAKLCHLKKS LQASRLRQLE NFHSRAESLA TNWKHITSAK
     RTIIHVPSLG YSQPRRLSLR GYDVLQNTQM GRLCDIRDEN VEVIYVSPVR LGEDVLQYYT
     RLLGLQTAIE LGDASATESH SAKRFTILMP EALEDFSTRN LCLASLLKYS PRTLKRIKNL
     IKGKQAYMIS GVTHTDDLAV ADELQIPLLG TDPVVTQLYS TKSGGKRIFS SAGVDMPPGK
     WDIYTLEKLY EGLAQLMAKH MEVQRWLFKI DSEVGGRGTA YVDVCHLKSR PWAQQEFIRH
     EPQQWRTSQS QDSVMIKFLE EVPHLLASYA RLANTSCYKT WACFLEHFLK EGGVIEAFPP
     SQSLTCLAVD LLLEPGGDVL MLSCGDQLRG PSGLEVLGCT VPQTSICPEV LHSVCTRVGQ
     ACQQRSIMGH ISLDLVTFLD PNNLEQQVWA IDLDLGYSNQ LAMTQLMLMM TRGTLNCRTS
     KLEVPPSETS VTSRFAVMCT RLLHTNLPLV YYSTFFLMCK AQGIGYDVKA RQGTVFALHD
     SRYRRSLGML TISENLQGAL LTFARNLSII HQEISAPNMQ GASNFKELIK DIEEVLGMTI
     QNQTASQEEK EITGVGSDWL STHKLHQHKM SQCTKPILQ