IQCJ_MOUSE
ID IQCJ_MOUSE Reviewed; 110 AA.
AC Q8BPW0;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=IQ domain-containing protein J {ECO:0000305};
GN Name=Iqcj {ECO:0000312|MGI:MGI:3644166};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Eye;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP ALTERNATIVE SPLICING.
RX PubMed=18550753; DOI=10.1523/jneurosci.1044-08.2008;
RA Martin P.M., Carnaud M., Garcia del Cano G., Irondelle M., Irinopoulou T.,
RA Girault J.A., Dargent B., Goutebroze L.;
RT "Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component
RT of nodes of Ranvier and axon initial segments.";
RL J. Neurosci. 28:6111-6117(2008).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=Iqcj-1;
CC IsoId=Q8BPW0-1; Sequence=Displayed;
CC Name=Iqcj-schip1-1; Synonyms=IQCJ-SCHIP-1;
CC IsoId=A0A088MLT8-1; Sequence=External;
CC Name=Iqcj-schip1-2;
CC IsoId=A0A088MLT8-2; Sequence=External;
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DR EMBL; AK052136; BAC34854.1; -; mRNA.
DR EMBL; BC107305; AAI07306.1; -; mRNA.
DR EMBL; BC107306; AAI07307.1; -; mRNA.
DR CCDS; CCDS57217.1; -. [Q8BPW0-1]
DR RefSeq; NP_808253.1; NM_177585.3. [Q8BPW0-1]
DR AlphaFoldDB; Q8BPW0; -.
DR STRING; 10090.ENSMUSP00000069544; -.
DR PhosphoSitePlus; Q8BPW0; -.
DR PaxDb; Q8BPW0; -.
DR PRIDE; Q8BPW0; -.
DR Antibodypedia; 54183; 147 antibodies from 19 providers.
DR Ensembl; ENSMUST00000063263; ENSMUSP00000069544; ENSMUSG00000051777. [Q8BPW0-1]
DR GeneID; 208426; -.
DR KEGG; mmu:208426; -.
DR UCSC; uc008plq.1; mouse. [Q8BPW0-1]
DR CTD; 654502; -.
DR MGI; MGI:3644166; Iqcj.
DR VEuPathDB; HostDB:ENSMUSG00000051777; -.
DR eggNOG; ENOG502S3HE; Eukaryota.
DR GeneTree; ENSGT00390000000847; -.
DR HOGENOM; CLU_150757_0_0_1; -.
DR InParanoid; Q8BPW0; -.
DR OMA; KYRINLQ; -.
DR PhylomeDB; Q8BPW0; -.
DR TreeFam; TF336256; -.
DR BioGRID-ORCS; 208426; 0 hits in 68 CRISPR screens.
DR Proteomes; UP000000589; Chromosome 3.
DR RNAct; Q8BPW0; protein.
DR Bgee; ENSMUSG00000051777; Expressed in floor plate and 20 other tissues.
DR InterPro; IPR029362; IQCJ-SCHIP1_N.
DR Pfam; PF15157; IQCJ-SCHIP1; 1.
PE 4: Predicted;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..110
FT /note="IQ domain-containing protein J"
FT /id="PRO_0000315662"
FT DOMAIN 47..67
FT /note="IQ"
FT REGION 63..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..99
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 110 AA; 12662 MW; 9CB40835661BB174 CRC64;
MRLEELKRLQ NPLEQVDDGK YLLENHQLAM DVENNIENYP LSLQPLESKV KIIQRAWREY
LQRQDPLEKR SPSPPSVSSD KLSSSVSMNT FSDSSTPVSV SRPLAWTVLH
