ID   IR10_HCMVM              Reviewed;         170 AA.
AC   F5HI32;
DT   11-JUL-2012, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   29-SEP-2021, entry version 24.
DE   RecName: Full=Protein IRL10;
DE            Short=TRL10;
DE   Flags: Precursor;
GN   Name=RL10;
OS   Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
OX   NCBI_TaxID=295027;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15105547; DOI=10.1099/vir.0.79888-0;
RA   Dolan A., Cunningham C., Hector R.D., Hassan-Walker A.F., Lee L.,
RA   Addison C., Dargan D.J., McGeoch D.J., Gatherer D., Emery V.C.,
RA   Griffiths P.D., Sinzger C., McSharry B.P., Wilkinson G.W.G., Davison A.J.;
RT   "Genetic content of wild-type human cytomegalovirus.";
RL   J. Gen. Virol. 85:1301-1312(2004).
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the HHV-5 RL10 protein family. {ECO:0000305}.
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DR   EMBL; AY446894; AAR31564.1; -; Genomic_DNA.
DR   RefSeq; YP_081458.1; NC_006273.2.
DR   SMR; F5HI32; -.
DR   PRIDE; F5HI32; -.
DR   DNASU; 3077518; -.
DR   GeneID; 3077518; -.
DR   KEGG; vg:3077518; -.
DR   Reactome; R-HSA-9609690; HCMV Early Events.
DR   Proteomes; UP000000938; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; TAS:Reactome.
DR   GO; GO:0019031; C:viral envelope; TAS:Reactome.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR009284; Cytomega_TRL10.
DR   Pfam; PF06084; Cytomega_TRL10; 1.
DR   PIRSF; PIRSF018454; Cytomega_TRL10; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix; Virion.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..170
FT                   /note="Protein IRL10"
FT                   /id="PRO_0000418309"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          132..170
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        48
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        55
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        107
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   170 AA;  18975 MW;  7C850AB8EF36E61C CRC64;
     MYPRVMHAVC FLALGLISYV AVCAENTVTT NCLVKAENTH LTCKCNPNTT SNTNNGSKCH
     AMCKCRVTEP ITMLGAYSAW GAGSFVATLI VLLVVFFVIY AREEEKNNTG TEVDQCLAYR
     SLTRKKLEQH AAKKQNIYER IPYRPSRQND NSPLIEPTGT DDEEDEDDDV