ID   IRAM_ECO27              Reviewed;         111 AA.
AC   B7UQ15;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Anti-adapter protein IraM {ECO:0000255|HAMAP-Rule:MF_01199};
GN   Name=iraM {ECO:0000255|HAMAP-Rule:MF_01199}; OrderedLocusNames=E2348C_1245;
OS   Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=574521;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2348/69 / EPEC;
RX   PubMed=18952797; DOI=10.1128/jb.01238-08;
RA   Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T., Henderson I.R.,
RA   Harris D., Asadulghani M., Kurokawa K., Dean P., Kenny B., Quail M.A.,
RA   Thurston S., Dougan G., Hayashi T., Parkhill J., Frankel G.;
RT   "Complete genome sequence and comparative genome analysis of
RT   enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL   J. Bacteriol. 191:347-354(2009).
CC   -!- FUNCTION: Inhibits RpoS proteolysis by regulating RssB activity,
CC       thereby increasing the stability of the sigma stress factor RpoS during
CC       magnesium starvation. {ECO:0000255|HAMAP-Rule:MF_01199}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01199}.
CC   -!- SIMILARITY: Belongs to the IraM/RssC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01199}.
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DR   EMBL; FM180568; CAS08793.1; -; Genomic_DNA.
DR   RefSeq; WP_000871291.1; NC_011601.1.
DR   AlphaFoldDB; B7UQ15; -.
DR   EnsemblBacteria; CAS08793; CAS08793; E2348C_1245.
DR   GeneID; 58391887; -.
DR   KEGG; ecg:E2348C_1245; -.
DR   HOGENOM; CLU_143527_1_0_6; -.
DR   OMA; LCPYGAR; -.
DR   Proteomes; UP000008205; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.50.650; -; 1.
DR   HAMAP; MF_01199; Anti_adapt_IraM; 1.
DR   InterPro; IPR014448; Anti-adapter_IraM.
DR   InterPro; IPR038679; PmrD_sf.
DR   PIRSF; PIRSF007036; Elb1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Stress response.
FT   CHAIN           1..111
FT                   /note="Anti-adapter protein IraM"
FT                   /id="PRO_1000164552"
SQ   SEQUENCE   111 AA;  12769 MW;  3B8A336958D5E7E3 CRC64;
     MKWIVIDTVI QPSCGISFSV IWSKIKLIIW YQSDAFLPPE SIFTLTHTGI MLNNKVLPVT
     IYNVVPFNKT FWNLIKNSQE CPTNTDNVLN ECFNNRCTLQ ICPYGLKQQS P