IRAM_ECODH
ID IRAM_ECODH Reviewed; 107 AA.
AC B1XA47;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 20-MAY-2008, sequence version 1.
DT 03-AUG-2022, entry version 58.
DE RecName: Full=Anti-adapter protein IraM {ECO:0000255|HAMAP-Rule:MF_01199};
GN Name=iraM {ECO:0000255|HAMAP-Rule:MF_01199};
GN OrderedLocusNames=ECDH10B_1209;
OS Escherichia coli (strain K12 / DH10B).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=316385;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / DH10B;
RX PubMed=18245285; DOI=10.1128/jb.01695-07;
RA Durfee T., Nelson R., Baldwin S., Plunkett G. III, Burland V., Mau B.,
RA Petrosino J.F., Qin X., Muzny D.M., Ayele M., Gibbs R.A., Csorgo B.,
RA Posfai G., Weinstock G.M., Blattner F.R.;
RT "The complete genome sequence of Escherichia coli DH10B: insights into the
RT biology of a laboratory workhorse.";
RL J. Bacteriol. 190:2597-2606(2008).
CC -!- FUNCTION: Inhibits RpoS proteolysis by regulating RssB activity,
CC thereby increasing the stability of the sigma stress factor RpoS during
CC magnesium starvation. {ECO:0000255|HAMAP-Rule:MF_01199}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01199}.
CC -!- SIMILARITY: Belongs to the IraM/RssC family. {ECO:0000255|HAMAP-
CC Rule:MF_01199}.
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DR EMBL; CP000948; ACB02330.1; -; Genomic_DNA.
DR RefSeq; WP_001295666.1; NC_010473.1.
DR AlphaFoldDB; B1XA47; -.
DR SMR; B1XA47; -.
DR KEGG; ecd:ECDH10B_1209; -.
DR HOGENOM; CLU_143527_1_0_6; -.
DR OMA; FSAIWGD; -.
DR BioCyc; ECOL316385:ECDH10B_RS06235-MON; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009267; P:cellular response to starvation; IEA:UniProtKB-UniRule.
DR Gene3D; 2.40.50.650; -; 1.
DR HAMAP; MF_01199; Anti_adapt_IraM; 1.
DR InterPro; IPR014448; Anti-adapter_IraM.
DR InterPro; IPR038679; PmrD_sf.
DR PIRSF; PIRSF007036; Elb1; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Stress response.
FT CHAIN 1..107
FT /note="Anti-adapter protein IraM"
FT /id="PRO_1000138498"
SQ SEQUENCE 107 AA; 12133 MW; 27F8A8C64FA18984 CRC64;
MKWIVIDTVI QPTCGISFSA IWGNMKMIIW YQSTIFLPPG SIFTPVKSGI ILKDKEYPIT
IYHIAPFNKD LWSLLKSSQE CPPGESKITN KCLHNSCIIK ICPYGLK