ID   IRAM_ECOLU              Reviewed;         107 AA.
AC   B7N3W1;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Anti-adapter protein IraM {ECO:0000255|HAMAP-Rule:MF_01199};
GN   Name=iraM {ECO:0000255|HAMAP-Rule:MF_01199}; OrderedLocusNames=ECUMN_1445;
OS   Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585056;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UMN026 / ExPEC;
RX   PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA   Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA   Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA   Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA   Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA   Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA   Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA   Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT   "Organised genome dynamics in the Escherichia coli species results in
RT   highly diverse adaptive paths.";
RL   PLoS Genet. 5:E1000344-E1000344(2009).
CC   -!- FUNCTION: Inhibits RpoS proteolysis by regulating RssB activity,
CC       thereby increasing the stability of the sigma stress factor RpoS during
CC       magnesium starvation. {ECO:0000255|HAMAP-Rule:MF_01199}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01199}.
CC   -!- SIMILARITY: Belongs to the IraM/RssC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01199}.
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DR   EMBL; CU928163; CAR12654.1; -; Genomic_DNA.
DR   RefSeq; WP_001309448.1; NC_011751.1.
DR   RefSeq; YP_002412192.1; NC_011751.1.
DR   AlphaFoldDB; B7N3W1; -.
DR   SMR; B7N3W1; -.
DR   STRING; 585056.ECUMN_1445; -.
DR   EnsemblBacteria; CAR12654; CAR12654; ECUMN_1445.
DR   KEGG; eum:ECUMN_1445; -.
DR   HOGENOM; CLU_143527_1_0_6; -.
DR   OMA; FSAIWGD; -.
DR   Proteomes; UP000007097; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.50.650; -; 1.
DR   HAMAP; MF_01199; Anti_adapt_IraM; 1.
DR   InterPro; IPR014448; Anti-adapter_IraM.
DR   InterPro; IPR038679; PmrD_sf.
PE   3: Inferred from homology;
KW   Cytoplasm; Stress response.
FT   CHAIN           1..107
FT                   /note="Anti-adapter protein IraM"
FT                   /id="PRO_1000138499"
SQ   SEQUENCE   107 AA;  12190 MW;  D243A40DED5FD098 CRC64;
     MKWIVIDTVI QPTCGISFSA IWGDMKMIIW YQPTIFLTPG SIFTPVKSGI IFKDKEYPIT
     IYNITPFNKD LWSLLKSSQE CPPGESEITN KCLHNSCIIK ICPYGLK