IRAM_ECOLX
ID IRAM_ECOLX Reviewed; 107 AA.
AC Q9EUE4; Q9EVQ0;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 53.
DE RecName: Full=Anti-adapter protein IraM;
GN Name=iraM;
OS Escherichia coli.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=1448/97, 3985/96, E32511, and Ed-147;
RX PubMed=10948097; DOI=10.1128/iai.68.9.4856-4864.2000;
RA Unkmeir A., Schmidt H.;
RT "Structural analysis of phage-borne stx genes and their flanking sequences
RT in shiga toxin-producing Escherichia coli and Shigella dysenteriae type 1
RT strains.";
RL Infect. Immun. 68:4856-4864(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=B2F1;
RX PubMed=12117937; DOI=10.1128/iai.70.8.4282-4291.2002;
RA Teel L.D., Melton-Celsa A.R., Schmitt C.K., O'Brien A.D.;
RT "One of two copies of the gene for the activatable shiga toxin type 2d in
RT Escherichia coli O91:H21 strain B2F1 is associated with an inducible
RT bacteriophage.";
RL Infect. Immun. 70:4282-4291(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=258/98;
RX PubMed=16517637; DOI=10.1128/aem.72.3.1900-1909.2006;
RA Bielaszewska M., Prager R., Zhang W., Friedrich A.W., Mellmann A.,
RA Tschape H., Karch H.;
RT "Chromosomal dynamism in progeny of outbreak-related sorbitol-fermenting
RT enterohemorrhagic Escherichia coli O157:NM.";
RL Appl. Environ. Microbiol. 72:1900-1909(2006).
CC -!- FUNCTION: Inhibits RpoS proteolysis by regulating RssB activity,
CC thereby increasing the stability of the sigma stress factor RpoS during
CC magnesium starvation. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the IraM/RssC family. {ECO:0000305}.
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DR EMBL; AF479828; AAM88311.1; -; Genomic_DNA.
DR EMBL; DQ231591; ABB60214.1; -; Genomic_DNA.
DR EMBL; DQ231595; ABB60238.1; -; Genomic_DNA.
DR EMBL; AJ250954; CAC05528.1; -; Genomic_DNA.
DR EMBL; AJ251452; CAC05542.1; -; Genomic_DNA.
DR EMBL; AJ251483; CAC05547.1; -; Genomic_DNA.
DR EMBL; AJ251520; CAC05551.1; -; Genomic_DNA.
DR RefSeq; WP_001303568.1; NZ_VODI01000385.1.
DR RefSeq; WP_001398907.1; NZ_RRNY01000081.1.
DR AlphaFoldDB; Q9EUE4; -.
DR SMR; Q9EUE4; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009267; P:cellular response to starvation; IEA:UniProtKB-UniRule.
DR Gene3D; 2.40.50.650; -; 1.
DR HAMAP; MF_01199; Anti_adapt_IraM; 1.
DR InterPro; IPR014448; Anti-adapter_IraM.
DR InterPro; IPR038679; PmrD_sf.
DR PIRSF; PIRSF007036; Elb1; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Stress response.
FT CHAIN 1..107
FT /note="Anti-adapter protein IraM"
FT /id="PRO_0000337882"
FT VARIANT 15
FT /note="D -> G (in strain: E32511)"
FT VARIANT 35
FT /note="I -> T (in strain: E32511)"
FT VARIANT 65
FT /note="T -> A (in strain: E32511)"
FT VARIANT 77
FT /note="S -> N (in strain: E32511)"
SQ SEQUENCE 107 AA; 12250 MW; 00DCAB9887D98307 CRC64;
MNWIVIDTVI QPACDISFSA IWCNIKLILW YQSDIFLPPG CIFTPTRTGV ILNNKELPVT
IYNVTPFNKN VWNLIKSSQE CPANTGNITD KCFNHRCILE ICPYGRK
