ID   IRAM_SHIFL              Reviewed;         111 AA.
AC   Q83L29;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Anti-adapter protein IraM {ECO:0000255|HAMAP-Rule:MF_01199};
GN   Name=iraM {ECO:0000255|HAMAP-Rule:MF_01199};
GN   OrderedLocusNames=SF1543, S4818.1;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Inhibits RpoS proteolysis by regulating RssB activity,
CC       thereby increasing the stability of the sigma stress factor RpoS during
CC       magnesium starvation. {ECO:0000255|HAMAP-Rule:MF_01199}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01199}.
CC   -!- SIMILARITY: Belongs to the IraM/RssC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01199}.
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DR   EMBL; AE005674; AAN43132.1; -; Genomic_DNA.
DR   EMBL; AE014073; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_707425.1; NC_004337.2.
DR   RefSeq; WP_000871291.1; NZ_WPGV01000177.1.
DR   AlphaFoldDB; Q83L29; -.
DR   STRING; 198214.SF1543; -.
DR   EnsemblBacteria; AAN43132; AAN43132; SF1543.
DR   GeneID; 1024726; -.
DR   GeneID; 58391887; -.
DR   KEGG; sfl:SF1543; -.
DR   PATRIC; fig|623.156.peg.381; -.
DR   HOGENOM; CLU_143527_1_0_6; -.
DR   OMA; LCPYGAR; -.
DR   OrthoDB; 1516718at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.50.650; -; 1.
DR   HAMAP; MF_01199; Anti_adapt_IraM; 1.
DR   InterPro; IPR014448; Anti-adapter_IraM.
DR   InterPro; IPR038679; PmrD_sf.
DR   PIRSF; PIRSF007036; Elb1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Stress response.
FT   CHAIN           1..111
FT                   /note="Anti-adapter protein IraM"
FT                   /id="PRO_0000337888"
SQ   SEQUENCE   111 AA;  12769 MW;  3B8A336958D5E7E3 CRC64;
     MKWIVIDTVI QPSCGISFSV IWSKIKLIIW YQSDAFLPPE SIFTLTHTGI MLNNKVLPVT
     IYNVVPFNKT FWNLIKNSQE CPTNTDNVLN ECFNNRCTLQ ICPYGLKQQS P