IRAP_CITK8
ID IRAP_CITK8 Reviewed; 86 AA.
AC A8AK82;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 1.
DT 03-AUG-2022, entry version 62.
DE RecName: Full=Anti-adapter protein IraP {ECO:0000255|HAMAP-Rule:MF_01198};
GN Name=iraP {ECO:0000255|HAMAP-Rule:MF_01198}; OrderedLocusNames=CKO_02790;
OS Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Citrobacter.
OX NCBI_TaxID=290338;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-895 / CDC 4225-83 / SGSC4696;
RG The Citrobacter koseri Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W.,
RA Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Inhibits RpoS proteolysis by regulating RssB activity,
CC thereby increasing the stability of the sigma stress factor RpoS
CC especially during phosphate starvation, but also in stationary phase
CC and during nitrogen starvation. Its effect on RpoS stability is due to
CC its interaction with RssB, which probably blocks the interaction of
CC RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to
CC the ClpXP protein degradation pathway. {ECO:0000255|HAMAP-
CC Rule:MF_01198}.
CC -!- SUBUNIT: Interacts with RssB. {ECO:0000255|HAMAP-Rule:MF_01198}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01198}.
CC -!- SIMILARITY: Belongs to the IraP family. {ECO:0000255|HAMAP-
CC Rule:MF_01198}.
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DR EMBL; CP000822; ABV13896.1; -; Genomic_DNA.
DR RefSeq; WP_012133608.1; NC_009792.1.
DR AlphaFoldDB; A8AK82; -.
DR SMR; A8AK82; -.
DR STRING; 290338.CKO_02790; -.
DR EnsemblBacteria; ABV13896; ABV13896; CKO_02790.
DR GeneID; 45136634; -.
DR KEGG; cko:CKO_02790; -.
DR HOGENOM; CLU_169517_0_0_6; -.
DR OMA; IDTAMIH; -.
DR OrthoDB; 2029093at2; -.
DR Proteomes; UP000008148; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009267; P:cellular response to starvation; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01198; Anti_adapt_IraP; 1.
DR InterPro; IPR019732; SigmaS_Anti-adapt_IraP.
DR Pfam; PF10796; Anti-adapt_IraP; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Reference proteome; Stress response.
FT CHAIN 1..86
FT /note="Anti-adapter protein IraP"
FT /id="PRO_0000337847"
FT COILED 1..36
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01198"
SQ SEQUENCE 86 AA; 9923 MW; B71DABDE903C169A CRC64;
MKNLISELLL RLAQKEEESK ELVAQVEALE IIVTAMLRNM AQNEQQKLIH QVEDALDGVK
PDASVPDYDT ELLRQYVKKL LRHPRS