ID   IRAP_KLEP7              Reviewed;          86 AA.
AC   A6T5A7;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Anti-adapter protein IraP {ECO:0000255|HAMAP-Rule:MF_01198};
GN   Name=iraP {ECO:0000255|HAMAP-Rule:MF_01198};
GN   OrderedLocusNames=KPN78578_03170; ORFNames=KPN_00326;
OS   Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=272620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700721 / MGH 78578;
RG   The Klebsiella pneumonia Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA   Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Inhibits RpoS proteolysis by regulating RssB activity,
CC       thereby increasing the stability of the sigma stress factor RpoS
CC       especially during phosphate starvation, but also in stationary phase
CC       and during nitrogen starvation. Its effect on RpoS stability is due to
CC       its interaction with RssB, which probably blocks the interaction of
CC       RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to
CC       the ClpXP protein degradation pathway. {ECO:0000255|HAMAP-
CC       Rule:MF_01198}.
CC   -!- SUBUNIT: Interacts with RssB. {ECO:0000255|HAMAP-Rule:MF_01198}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01198}.
CC   -!- SIMILARITY: Belongs to the IraP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01198}.
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DR   EMBL; CP000647; ABR75778.1; -; Genomic_DNA.
DR   RefSeq; WP_002890221.1; NC_009648.1.
DR   AlphaFoldDB; A6T5A7; -.
DR   SMR; A6T5A7; -.
DR   STRING; 272620.KPN_00326; -.
DR   jPOST; A6T5A7; -.
DR   EnsemblBacteria; ABR75778; ABR75778; KPN_00326.
DR   KEGG; kpn:KPN_00326; -.
DR   HOGENOM; CLU_169517_0_0_6; -.
DR   OMA; IDTAMIH; -.
DR   Proteomes; UP000000265; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01198; Anti_adapt_IraP; 1.
DR   InterPro; IPR019732; SigmaS_Anti-adapt_IraP.
DR   Pfam; PF10796; Anti-adapt_IraP; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Reference proteome; Stress response.
FT   CHAIN           1..86
FT                   /note="Anti-adapter protein IraP"
FT                   /id="PRO_0000337857"
FT   COILED          1..38
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01198"
SQ   SEQUENCE   86 AA;  9845 MW;  2ABB29B7572E4D29 CRC64;
     MKNLIAELLV KLAQKEEEAK ELTVQVEALE IVVTALLRHM EHDAQQALIQ DIEQAIDQVT
     PCPPVNDHDA MLLQQYLKKL LRHPRS