ID   IRAP_SHIDS              Reviewed;          86 AA.
AC   Q32JD0;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Anti-adapter protein IraP {ECO:0000255|HAMAP-Rule:MF_01198};
GN   Name=iraP {ECO:0000255|HAMAP-Rule:MF_01198}; OrderedLocusNames=SDY_0363;
OS   Shigella dysenteriae serotype 1 (strain Sd197).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300267;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sd197;
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J.,
RA   Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J.,
RA   Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J.,
RA   Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic agents of
RT   bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- FUNCTION: Inhibits RpoS proteolysis by regulating RssB activity,
CC       thereby increasing the stability of the sigma stress factor RpoS
CC       especially during phosphate starvation, but also in stationary phase
CC       and during nitrogen starvation. Its effect on RpoS stability is due to
CC       its interaction with RssB, which probably blocks the interaction of
CC       RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to
CC       the ClpXP protein degradation pathway. {ECO:0000255|HAMAP-
CC       Rule:MF_01198}.
CC   -!- SUBUNIT: Interacts with RssB. {ECO:0000255|HAMAP-Rule:MF_01198}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01198}.
CC   -!- SIMILARITY: Belongs to the IraP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01198}.
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DR   EMBL; CP000034; ABB60577.1; -; Genomic_DNA.
DR   RefSeq; WP_000792965.1; NC_007606.1.
DR   RefSeq; YP_402066.1; NC_007606.1.
DR   AlphaFoldDB; Q32JD0; -.
DR   SMR; Q32JD0; -.
DR   STRING; 300267.SDY_0363; -.
DR   EnsemblBacteria; ABB60577; ABB60577; SDY_0363.
DR   KEGG; sdy:SDY_0363; -.
DR   PATRIC; fig|300267.13.peg.428; -.
DR   HOGENOM; CLU_169517_0_0_6; -.
DR   OMA; IDTAMIH; -.
DR   Proteomes; UP000002716; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01198; Anti_adapt_IraP; 1.
DR   InterPro; IPR019732; SigmaS_Anti-adapt_IraP.
DR   Pfam; PF10796; Anti-adapt_IraP; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Reference proteome; Stress response.
FT   CHAIN           1..86
FT                   /note="Anti-adapter protein IraP"
FT                   /id="PRO_0000337865"
FT   COILED          2..36
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01198"
SQ   SEQUENCE   86 AA;  9923 MW;  061DC9028C986BEE CRC64;
     MKNLIAELLF KLALKEEESK ELCAQVEALE IIVTAMLRNM AQNDQQRLID QVEGALYEVK
     PDASIPDDDT ELLRDYVKKL LKHPRQ