ID   IRC19_ASHGO             Reviewed;         213 AA.
AC   Q753Y5;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Increased recombination centers protein 19;
GN   Name=IRC19; Synonyms=RRG4; OrderedLocusNames=AFR187C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Involved in sporulation and maintenance of the mitochondrial
CC       DNA. Is probably involved in a pathway contributing to genomic
CC       integrity (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IRC19 family. {ECO:0000305}.
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DR   EMBL; AE016819; AAS53558.1; -; Genomic_DNA.
DR   RefSeq; NP_985734.1; NM_211088.1.
DR   AlphaFoldDB; Q753Y5; -.
DR   STRING; 33169.AAS53558; -.
DR   EnsemblFungi; AAS53558; AAS53558; AGOS_AFR187C.
DR   GeneID; 4621992; -.
DR   KEGG; ago:AGOS_AFR187C; -.
DR   eggNOG; ENOG502S35W; Eukaryota.
DR   HOGENOM; CLU_106818_0_0_1; -.
DR   InParanoid; Q753Y5; -.
DR   OMA; FMRLKPF; -.
DR   Proteomes; UP000000591; Chromosome VI.
DR   GO; GO:0030437; P:ascospore formation; IEA:EnsemblFungi.
DR   GO; GO:0006312; P:mitotic recombination; IEA:EnsemblFungi.
DR   InterPro; IPR016613; Irc19.
DR   PIRSF; PIRSF013329; UCP013329; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Sporulation.
FT   CHAIN           1..213
FT                   /note="Increased recombination centers protein 19"
FT                   /id="PRO_0000399057"
SQ   SEQUENCE   213 AA;  24903 MW;  75188607F4751B0E CRC64;
     MLPLAIPPNN IVRAMSSPNA TGPLMRTSKA IITSNYTLLT DKTPYLLPVC FNESCRAEQV
     RMLYRRFFRL RPLVAQRAMI KESYTNYIRV KFSEDYALKR RQALPQNTCP VLDAIEAGRR
     SLTFILKAVS EIEDADSNPE LAYDNYICRK ILKNVLTLEY QRERLEFKNP KRKQILRQNY
     EYLDAKYHDP KYTSLRNADV SIIHFNETLG TRL