ID   IRC19_KLULA             Reviewed;         188 AA.
AC   Q6CQ02;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Increased recombination centers protein 19;
GN   Name=IRC19; Synonyms=RRG4; OrderedLocusNames=KLLA0E00859g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in sporulation and maintenance of the mitochondrial
CC       DNA. Is probably involved in a pathway contributing to genomic
CC       integrity (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IRC19 family. {ECO:0000305}.
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DR   EMBL; CR382125; CAG99074.1; -; Genomic_DNA.
DR   RefSeq; XP_453987.1; XM_453987.1.
DR   AlphaFoldDB; Q6CQ02; -.
DR   SMR; Q6CQ02; -.
DR   STRING; 28985.XP_453987.1; -.
DR   EnsemblFungi; CAG99074; CAG99074; KLLA0_E00859g.
DR   GeneID; 2894001; -.
DR   KEGG; kla:KLLA0_E00859g; -.
DR   eggNOG; ENOG502S35W; Eukaryota.
DR   HOGENOM; CLU_106818_0_0_1; -.
DR   InParanoid; Q6CQ02; -.
DR   OMA; FMRLKPF; -.
DR   Proteomes; UP000000598; Chromosome E.
DR   GO; GO:0030437; P:ascospore formation; IEA:EnsemblFungi.
DR   GO; GO:0006312; P:mitotic recombination; IEA:EnsemblFungi.
DR   InterPro; IPR016613; Irc19.
DR   PIRSF; PIRSF013329; UCP013329; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Sporulation.
FT   CHAIN           1..188
FT                   /note="Increased recombination centers protein 19"
FT                   /id="PRO_0000399059"
SQ   SEQUENCE   188 AA;  22311 MW;  CA776D13E70CD690 CRC64;
     MVLIKSRKSI VTATNVCINS SSKFYLTEEQ VQSLGDKEFL TASYRRFLRM RQFISKRQMV
     KESYTTYLRY KFKIEDFELK RSKLLSVSGM SAMDFRSSVQ KSLCFLIKAF SISDAYSKDM
     IDDSHKCKKI IKNLLTVDYH RNRIINRSSN MYQYYRKDFT FFTDGQNIGL KQFEENLMRL
     NECLGTRL