ID   IRC6_CANAW              Reviewed;         275 AA.
AC   C4YH38;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 35.
DE   RecName: Full=Increased recombination centers protein 6;
GN   Name=IRC6; ORFNames=CAWG_03379;
OS   Candida albicans (strain WO-1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294748;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WO-1;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Involved in gross chromosomal rearrangements (GCRs) and
CC       telomere healing. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IRC6 family. {ECO:0000305}.
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DR   EMBL; CH672349; EEQ45070.1; -; Genomic_DNA.
DR   AlphaFoldDB; C4YH38; -.
DR   SMR; C4YH38; -.
DR   EnsemblFungi; EEQ45070; EEQ45070; CAWG_03379.
DR   VEuPathDB; FungiDB:CAWG_03379; -.
DR   HOGENOM; CLU_064540_0_0_1; -.
DR   OMA; GLMFTIN; -.
DR   Proteomes; UP000001429; Chromosome 4, Supercontig 1.4.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR034627; Irc6.
DR   PANTHER; PTHR28043; PTHR28043; 1.
PE   3: Inferred from homology;
KW   Chromosomal rearrangement.
FT   CHAIN           1..275
FT                   /note="Increased recombination centers protein 6"
FT                   /id="PRO_0000399217"
SQ   SEQUENCE   275 AA;  31799 MW;  836EFACAD43F2392 CRC64;
     MIPNHILILG SPNSGKLRIA NLISKNEEIP NLEDVELHSG LIVKASLRTK YYFLKLNILI
     DEYSESKGAT DEKKLSELHK WYQEFKSEEF GELREVLDGL MFTINMKTDS ISFIRDALEI
     IEQIKISLGD EENLHDWGGF IAVVGSCPEN QIVEDDLILE IEDMVLSQGL EFINLSTEGE
     NEYKEKQGKD RIVELIESHD WTNLEMLKVD SKQYETNKLA KMESMKQKLI NEKEELDLDD
     IFSKLNLARD HAQSLTQDER DKYANKVIEE IIDFL