ID   IRC6_CANGA              Reviewed;         265 AA.
AC   Q6FWX8;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Increased recombination centers protein 6;
GN   Name=IRC6; OrderedLocusNames=CAGL0C02079g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in gross chromosomal rearrangements (GCRs) and
CC       telomere healing. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IRC6 family. {ECO:0000305}.
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DR   EMBL; CR380949; CAG58172.1; -; Genomic_DNA.
DR   RefSeq; XP_445266.1; XM_445266.1.
DR   AlphaFoldDB; Q6FWX8; -.
DR   SMR; Q6FWX8; -.
DR   STRING; 5478.XP_445266.1; -.
DR   EnsemblFungi; CAG58172; CAG58172; CAGL0C02079g.
DR   GeneID; 2886863; -.
DR   KEGG; cgr:CAGL0C02079g; -.
DR   CGD; CAL0127220; CAGL0C02079g.
DR   VEuPathDB; FungiDB:CAGL0C02079g; -.
DR   eggNOG; ENOG502S7AE; Eukaryota.
DR   HOGENOM; CLU_079666_0_0_1; -.
DR   InParanoid; Q6FWX8; -.
DR   OMA; GLMFTIN; -.
DR   Proteomes; UP000002428; Chromosome C.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR034627; Irc6.
DR   PANTHER; PTHR28043; PTHR28043; 1.
PE   3: Inferred from homology;
KW   Chromosomal rearrangement; Reference proteome.
FT   CHAIN           1..265
FT                   /note="Increased recombination centers protein 6"
FT                   /id="PRO_0000399219"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   265 AA;  30313 MW;  D28D91C1EA81761A CRC64;
     MLDESSSSDE SRATELPVSS EDECEEVTDA KVLPNKVLVV FEGESTLFRD QLLDTVFGVQ
     DQGNIVKQLS WDTKYYAVEY DLYVDECVDI HGWLNEVNSD DYEELRDLLT MIIIVRSFDS
     TQDTKEYNSV LYDFIQGNSV SVISVNTNSA RQVKDTYDEF LELDASSIEF INYHDDRVEK
     ETNECKGMAR LKEIIDTHPW TDCKVVLKNK ESTSDKVNKP DLEYLIDTLK KAKIHYQKLS
     NGSDGFSEEA EQFALQMATD IANNL