ID   IRC6_CANTT              Reviewed;         275 AA.
AC   C5M2I3;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 29.
DE   RecName: Full=Increased recombination centers protein 6;
GN   Name=IRC6; ORFNames=CTRG_00272;
OS   Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294747;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-3404 / T1;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Involved in gross chromosomal rearrangements (GCRs) and
CC       telomere healing. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IRC6 family. {ECO:0000305}.
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DR   EMBL; GG692395; EER35533.1; -; Genomic_DNA.
DR   RefSeq; XP_002545491.1; XM_002545445.1.
DR   AlphaFoldDB; C5M2I3; -.
DR   SMR; C5M2I3; -.
DR   EnsemblFungi; EER35533; EER35533; CTRG_00272.
DR   GeneID; 8301227; -.
DR   KEGG; ctp:CTRG_00272; -.
DR   VEuPathDB; FungiDB:CTRG_00272; -.
DR   eggNOG; ENOG502SAXB; Eukaryota.
DR   HOGENOM; CLU_064540_0_0_1; -.
DR   OrthoDB; 1618204at2759; -.
DR   Proteomes; UP000002037; Unassembled WGS sequence.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR034627; Irc6.
DR   PANTHER; PTHR28043; PTHR28043; 1.
PE   3: Inferred from homology;
KW   Chromosomal rearrangement; Reference proteome.
FT   CHAIN           1..275
FT                   /note="Increased recombination centers protein 6"
FT                   /id="PRO_0000399220"
SQ   SEQUENCE   275 AA;  31904 MW;  D973426C0B00593C CRC64;
     MIPNHILILG SPNSGKLRVS KLISNDKDFP EIKENESHSG IIIKTSLSTK YYHIKLNILI
     DEYPEERNKS VTDEEKLLEL EKWFNEFKSE EFGELREVLD GLVFTVNMKA DSLEFIEKAL
     ETVSEIRTSL GDEESQWDGF ISIIGSTTQG ESVDDDTVEE IEDLVITHGF EFINLNTQGI
     NEFKEKQGKD RVVELIESHE WTNMELLKVN PDQYEKNKMN KVEQMKQNLL EEKESMDLDV
     VFSKLSVAKE RAEDMTQEQK EKYANEIIEE IIDFI