ID   IRC6_CLAL4              Reviewed;         268 AA.
AC   C4Y6U0;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 30.
DE   RecName: Full=Increased recombination centers protein 6;
GN   Name=IRC6; ORFNames=CLUG_03874;
OS   Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Metschnikowiaceae; Clavispora.
OX   NCBI_TaxID=306902;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42720;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Involved in gross chromosomal rearrangements (GCRs) and
CC       telomere healing. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IRC6 family. {ECO:0000305}.
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DR   EMBL; CH408079; EEQ39746.1; -; Genomic_DNA.
DR   RefSeq; XP_002616633.1; XM_002616587.1.
DR   AlphaFoldDB; C4Y6U0; -.
DR   SMR; C4Y6U0; -.
DR   EnsemblFungi; EEQ39746; EEQ39746; CLUG_03874.
DR   GeneID; 8497091; -.
DR   KEGG; clu:CLUG_03874; -.
DR   VEuPathDB; FungiDB:CLUG_03874; -.
DR   HOGENOM; CLU_064540_0_0_1; -.
DR   InParanoid; C4Y6U0; -.
DR   OMA; GLMFTIN; -.
DR   Proteomes; UP000007703; Unassembled WGS sequence.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR034627; Irc6.
DR   PANTHER; PTHR28043; PTHR28043; 1.
PE   3: Inferred from homology;
KW   Chromosomal rearrangement; Reference proteome.
FT   CHAIN           1..268
FT                   /note="Increased recombination centers protein 6"
FT                   /id="PRO_0000399221"
SQ   SEQUENCE   268 AA;  31329 MW;  3D3F57EBB15F4107 CRC64;
     MDRNNVLVLG PPKSGKIRFA QFISGDYETE TISDDSHSGL MYKCNLKTKY FSVDVNLLIE
     EFPESRKEPE EKWISSLQTW FGEFESDTMA DLREVIEGVV FTVCVNEWDD NVIKQQLDIL
     SNMKDLLKDN DPFFIVMGVS EHDIEQDTMA DLEDLVLLNG FEFVYFNDSG MNEFRDKMGK
     DRLLEVLETH EWTQKHLTHV SNEDYMAYKK EKMTSMTQGL LQEDDCNIPT LDVLLQKLQI
     EKSKVEEMKE NERKGYVDGL VDEFLEYF