ID   IRC6_LACTC              Reviewed;         251 AA.
AC   C5DLJ0;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=Increased recombination centers protein 6;
GN   Name=IRC6; OrderedLocusNames=KLTH0G01100g;
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Involved in gross chromosomal rearrangements (GCRs) and
CC       telomere healing. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IRC6 family. {ECO:0000305}.
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DR   EMBL; CU928171; CAR24651.1; -; Genomic_DNA.
DR   RefSeq; XP_002555088.1; XM_002555042.1.
DR   AlphaFoldDB; C5DLJ0; -.
DR   SMR; C5DLJ0; -.
DR   STRING; 559295.C5DLJ0; -.
DR   EnsemblFungi; CAR24651; CAR24651; KLTH0G01100g.
DR   GeneID; 8293346; -.
DR   KEGG; lth:KLTH0G01100g; -.
DR   eggNOG; ENOG502S7AE; Eukaryota.
DR   HOGENOM; CLU_079666_0_0_1; -.
DR   InParanoid; C5DLJ0; -.
DR   OMA; GLMFTIN; -.
DR   OrthoDB; 1618204at2759; -.
DR   Proteomes; UP000002036; Chromosome G.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR034627; Irc6.
DR   PANTHER; PTHR28043; PTHR28043; 1.
PE   3: Inferred from homology;
KW   Chromosomal rearrangement; Reference proteome.
FT   CHAIN           1..251
FT                   /note="Increased recombination centers protein 6"
FT                   /id="PRO_0000399223"
SQ   SEQUENCE   251 AA;  28309 MW;  19FEAB8514FBC4A7 CRC64;
     MTTGLSLDEG KVIEGRPKAL RDKVLIVFSN KVFNREEILF EVFGVEDNAG KQVHRGVDWT
     TKYYTVTIDV YVDSFSNLED WTNEFCDPDF DELRDVIAGW IIVLPFSGNI EEETKALSRL
     VNNATSEDFF TAILATELNV GKNERAFLEY NVLAGAVELV HNELDSDGEL KEVNGVDRVK
     EIIDTCDWHP RLLRTAHLES ETGMESACTG ISLAQIMGSL REARTKYMAM DPGLDREEFA
     NEMANELSKL L