ID   IRC6_PICGU              Reviewed;         277 AA.
AC   A5DMM1;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 2.
DT   03-AUG-2022, entry version 37.
DE   RecName: Full=Increased recombination centers protein 6;
GN   Name=IRC6; ORFNames=PGUG_04522;
OS   Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS   / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX   NCBI_TaxID=294746;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Involved in gross chromosomal rearrangements (GCRs) and
CC       telomere healing. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IRC6 family. {ECO:0000305}.
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DR   EMBL; CH408159; EDK40424.2; -; Genomic_DNA.
DR   RefSeq; XP_001483793.1; XM_001483743.1.
DR   AlphaFoldDB; A5DMM1; -.
DR   EnsemblFungi; EDK40424; EDK40424; PGUG_04522.
DR   GeneID; 5125088; -.
DR   KEGG; pgu:PGUG_04522; -.
DR   VEuPathDB; FungiDB:PGUG_04522; -.
DR   eggNOG; ENOG502SAXB; Eukaryota.
DR   HOGENOM; CLU_064540_0_0_1; -.
DR   InParanoid; A5DMM1; -.
DR   OMA; GLMFTIN; -.
DR   OrthoDB; 1618204at2759; -.
DR   Proteomes; UP000001997; Unassembled WGS sequence.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR034627; Irc6.
DR   PANTHER; PTHR28043; PTHR28043; 1.
PE   3: Inferred from homology;
KW   Chromosomal rearrangement; Reference proteome.
FT   CHAIN           1..277
FT                   /note="Increased recombination centers protein 6"
FT                   /id="PRO_0000399224"
SQ   SEQUENCE   277 AA;  31285 MW;  794AF0E1ABAD28D8 CRC64;
     MAQNNVLVLG APHSGKLRAS AIIGAGFSGD GDFSGSHSGL IFKIKRQTKY FKHDLSIMVD
     EYPEKRTITP SWEHLNAWSD EFMSEDMEEL RRALDGIVFC LNLDDKATMK DLEPTIGVLE
     KIYESLGGAE WAGFFAIVGV SSSEDNENHA IVEDAATIRG FEYINLEEEG QNEFRDKLGI
     DRLVELFDTH DWSDIETSED DGFAARKRKM AESMCQRLLD DDEKDMSSEN GVNDVNVEEF
     ENVIEKLKQA RIKAESMEGA ERNEYAQQVM EDVLSYL