ID   IRC6_VANPO              Reviewed;         250 AA.
AC   A7TQS6;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Increased recombination centers protein 6;
GN   Name=IRC6; ORFNames=Kpol_460p10;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: Involved in gross chromosomal rearrangements (GCRs) and
CC       telomere healing. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IRC6 family. {ECO:0000305}.
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DR   EMBL; DS480463; EDO15375.1; -; Genomic_DNA.
DR   RefSeq; XP_001643233.1; XM_001643183.1.
DR   AlphaFoldDB; A7TQS6; -.
DR   SMR; A7TQS6; -.
DR   STRING; 436907.A7TQS6; -.
DR   EnsemblFungi; EDO15375; EDO15375; Kpol_460p10.
DR   GeneID; 5543446; -.
DR   KEGG; vpo:Kpol_460p10; -.
DR   eggNOG; ENOG502S7AE; Eukaryota.
DR   HOGENOM; CLU_079666_0_0_1; -.
DR   InParanoid; A7TQS6; -.
DR   OMA; GLMFTIN; -.
DR   OrthoDB; 1618204at2759; -.
DR   PhylomeDB; A7TQS6; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR034627; Irc6.
DR   PANTHER; PTHR28043; PTHR28043; 1.
PE   3: Inferred from homology;
KW   Chromosomal rearrangement; Reference proteome.
FT   CHAIN           1..250
FT                   /note="Increased recombination centers protein 6"
FT                   /id="PRO_0000399225"
SQ   SEQUENCE   250 AA;  29069 MW;  E736880C5FC1F770 CRC64;
     MNEDGSVCNK ILIAFQDNDQ IANLKESVLG EVFRLDKANT NHDENIIKGL TWSTKYYEVR
     YDLYVDTFDD FEEWCKDLIS SEYDDLREVL SGIIVIDSYT MEKDKIDQNK LLGQLGSVLQ
     DKFFVFMNTN KDISQDVIDE LNDDNSMQLT SDSGNSVEII NYHNVSNLKL NQYNEKIGFE
     RVREIIDTCE WSGGHRVQTV EAKADSTDVD LESVFNRLKE ARLKYLEIED EDEREQFALE
     ISNEFAEFLQ