ID   APRL5_ARATH             Reviewed;         300 AA.
AC   Q93YX4; Q9SRW3;
DT   02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=5'-adenylylsulfate reductase-like 5;
DE   AltName: Full=Adenosine 5'-phosphosulfate reductase-like 5;
DE            Short=APR-like 5;
DE            Short=AtAPRL5;
DE   Flags: Precursor;
GN   Name=APRL5; OrderedLocusNames=At3g03860; ORFNames=F20H23.9;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130713; DOI=10.1038/35048706;
RA   Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA   Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA   Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA   Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA   Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA   Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA   Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA   Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA   Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA   Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA   Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA   de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA   Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA   Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA   Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA   Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA   Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA   Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA   Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA   Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA   Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA   Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA   Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL   Nature 408:820-822(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF00632.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC009540; AAF00632.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002686; AEE74004.1; -; Genomic_DNA.
DR   EMBL; AY059721; AAL24078.1; -; mRNA.
DR   EMBL; AY091351; AAM14290.1; -; mRNA.
DR   RefSeq; NP_566214.1; NM_111257.4.
DR   AlphaFoldDB; Q93YX4; -.
DR   SMR; Q93YX4; -.
DR   STRING; 3702.AT3G03860.1; -.
DR   PaxDb; Q93YX4; -.
DR   PRIDE; Q93YX4; -.
DR   ProteomicsDB; 244409; -.
DR   EnsemblPlants; AT3G03860.1; AT3G03860.1; AT3G03860.
DR   GeneID; 821101; -.
DR   Gramene; AT3G03860.1; AT3G03860.1; AT3G03860.
DR   KEGG; ath:AT3G03860; -.
DR   Araport; AT3G03860; -.
DR   TAIR; locus:2079439; AT3G03860.
DR   eggNOG; KOG2640; Eukaryota.
DR   HOGENOM; CLU_051582_1_0_1; -.
DR   OMA; IWHVNLA; -.
DR   OrthoDB; 1057290at2759; -.
DR   PhylomeDB; Q93YX4; -.
DR   PRO; PR:Q93YX4; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q93YX4; baseline and differential.
DR   Genevisible; Q93YX4; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR044794; APRL5/7.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR47126; PTHR47126; 1.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..300
FT                   /note="5'-adenylylsulfate reductase-like 5"
FT                   /id="PRO_0000400042"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          41..161
FT                   /note="Thioredoxin"
FT   CARBOHYD        136
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   300 AA;  33650 MW;  B6FC2390C69E663A CRC64;
     MDSRVSILFV CAIAVSCFTS GSASSPVDFS VCNYEFELFR FDLEAKCPPS LYPTPPIEVD
     GDSLDRLMAS QHGNAYMSVL FYASWCPFSR AVRPKFDMLS SMFPQIQHLA VEHSQALPSV
     FSRYGIHSLP SILMVNQTLN ARYHGRKDLI SLIEFYEEAT GLQPVQYVAE GEPTGLNAGD
     GNLITWLRKG TSIREIFKQD PFLVLSLLFI CLQMAILVFP IAESRMRALW ASYVANLNLG
     RFGEISQLFN RGIHMVDVRR LWLKLSLVKT RNFHERAKNA QAWASSLASV SLGQTSSDQS