ID   APRR4_ARATH             Reviewed;         292 AA.
AC   Q9FJ16;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 144.
DE   RecName: Full=Putative two-component response regulator-like APRR4;
DE   AltName: Full=Pseudo-response regulator 4;
GN   Name=APRR4; OrderedLocusNames=At5g49240; ORFNames=K21P3.12;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA   Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT   features of the regions of 1,081,958 bp covered by seventeen physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:379-391(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=10945350; DOI=10.1093/pcp/41.6.791;
RA   Makino S., Kiba T., Imamura A., Hanaki N., Nakamura A., Suzuki T.,
RA   Taniguchi M., Ueguchi C., Sugiyama T., Mizuno T.;
RT   "Genes encoding pseudo-response regulators: insight into His-to-Asp
RT   phosphorelay and circadian rhythm in Arabidopsis thaliana.";
RL   Plant Cell Physiol. 41:791-803(2000).
CC   -!- FUNCTION: Transcriptional activator that binds specifically to the DNA
CC       sequence 5'-[AG]GATT-3'. {ECO:0000250}.
CC   -!- SUBUNIT: Binds the target DNA as a monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ARR-like family. {ECO:0000305}.
CC   -!- CAUTION: Lacks the phospho-accepting Asp (here Gln-94), present in the
CC       receiver domain, which is one of the conserved features of the two-
CC       component response regulators (ARRs) family. {ECO:0000305}.
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DR   EMBL; AB016872; BAB10342.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED95788.1; -; Genomic_DNA.
DR   RefSeq; NP_199735.1; NM_124301.1.
DR   AlphaFoldDB; Q9FJ16; -.
DR   SMR; Q9FJ16; -.
DR   STRING; 3702.AT5G49240.1; -.
DR   PaxDb; Q9FJ16; -.
DR   PRIDE; Q9FJ16; -.
DR   EnsemblPlants; AT5G49240.1; AT5G49240.1; AT5G49240.
DR   GeneID; 834984; -.
DR   Gramene; AT5G49240.1; AT5G49240.1; AT5G49240.
DR   KEGG; ath:AT5G49240; -.
DR   Araport; AT5G49240; -.
DR   TAIR; locus:2155954; AT5G49240.
DR   eggNOG; KOG1601; Eukaryota.
DR   HOGENOM; CLU_061273_1_0_1; -.
DR   InParanoid; Q9FJ16; -.
DR   OMA; HNDRACA; -.
DR   OrthoDB; 767773at2759; -.
DR   PhylomeDB; Q9FJ16; -.
DR   PRO; PR:Q9FJ16; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FJ16; baseline and differential.
DR   Genevisible; Q9FJ16; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0009736; P:cytokinin-activated signaling pathway; IEA:InterPro.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   InterPro; IPR045279; ARR-like.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006447; Myb_dom_plants.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   PANTHER; PTHR43874; PTHR43874; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   TIGRFAMs; TIGR01557; myb_SHAQKYF; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..292
FT                   /note="Putative two-component response regulator-like
FT                   APRR4"
FT                   /id="PRO_0000132305"
FT   DOMAIN          43..158
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DNA_BIND        225..275
FT                   /note="Myb-like GARP"
FT   REGION          168..215
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        180..198
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        199..215
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   292 AA;  33818 MW;  AF025DBB1A0174D5 CRC64;
     MQPLNMAEIL DHRGVLTDGD DGPFRNLTNF YDMFSSNFPE GLRVLVFDED PSYLLILERH
     LQKFQYQVTI CNEVNKAMHT LRNHRNRFDL AMIQVNNAEG DIFRFLSEIG SEMDLPIIII
     SEDDSVKSVK KWMINGAADY LIKPIRPEDL RIVFKHLVKK MRERRSVVTG EAEKAAGEKS
     SSVGDSTIRN PNKSKRSSCL EAEVNEEDRH DHNDRACASS AKKRRVVWDE ELHQNFLNAV
     DFLGLERAVP KKILDVMKVD YISRENVASH LQVTFLIYNI IVHFQQHFCF YS