ID   ISAB_STAAC              Reviewed;         175 AA.
AC   Q5HCQ9;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Immunodominant staphylococcal antigen B;
DE   Flags: Precursor;
GN   Name=isaB; OrderedLocusNames=SACOL2660;
OS   Staphylococcus aureus (strain COL).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93062;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=COL;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IsaB family. {ECO:0000305}.
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DR   EMBL; CP000046; AAW38658.1; -; Genomic_DNA.
DR   RefSeq; WP_001044560.1; NC_002951.2.
DR   AlphaFoldDB; Q5HCQ9; -.
DR   SMR; Q5HCQ9; -.
DR   EnsemblBacteria; AAW38658; AAW38658; SACOL2660.
DR   KEGG; sac:SACOL2660; -.
DR   HOGENOM; CLU_119552_0_0_9; -.
DR   OMA; WYKYNGY; -.
DR   Proteomes; UP000000530; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Secreted; Signal.
FT   SIGNAL          1..36
FT                   /evidence="ECO:0000250"
FT   CHAIN           37..175
FT                   /note="Immunodominant staphylococcal antigen B"
FT                   /id="PRO_0000272665"
SQ   SEQUENCE   175 AA;  19370 MW;  D8C994A216EF3BB3 CRC64;
     MNKTSKVCVA ATLALGTLIG VTVVENSAPT SKQAQAAITP YYTYNGYIGN NANFILDKNF
     INAIKYDNVK FNGIKLAKTN TIKKVEKYDQ TFKGVSAKGN EASQLQFVVK NNISLKDIQK
     AYGKDLKKEN GKTKEADSGI FYYQNAKKTL GIWFVVDHNR VVEVTVGHTP YKTSK