ID   ISAB_STAAN              Reviewed;         175 AA.
AC   Q7A377;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Immunodominant staphylococcal antigen B;
DE   Flags: Precursor;
GN   Name=isaB; OrderedLocusNames=SA2431;
OS   Staphylococcus aureus (strain N315).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N315;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=N315;
RA   Vaezzadeh A.R., Deshusses J., Lescuyer P., Hochstrasser D.F.;
RT   "Shotgun proteomic analysis of total and membrane protein extracts of S.
RT   aureus strain N315.";
RL   Submitted (OCT-2007) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IsaB family. {ECO:0000305}.
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DR   EMBL; BA000018; BAB43736.1; -; Genomic_DNA.
DR   PIR; F90071; F90071.
DR   RefSeq; WP_001044560.1; NC_002745.2.
DR   AlphaFoldDB; Q7A377; -.
DR   SMR; Q7A377; -.
DR   EnsemblBacteria; BAB43736; BAB43736; BAB43736.
DR   KEGG; sau:SA2431; -.
DR   HOGENOM; CLU_119552_0_0_9; -.
DR   OMA; WYKYNGY; -.
DR   Proteomes; UP000000751; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Secreted; Signal.
FT   SIGNAL          1..36
FT                   /evidence="ECO:0000250"
FT   CHAIN           37..175
FT                   /note="Immunodominant staphylococcal antigen B"
FT                   /id="PRO_0000272667"
SQ   SEQUENCE   175 AA;  19370 MW;  D8C994A216EF3BB3 CRC64;
     MNKTSKVCVA ATLALGTLIG VTVVENSAPT SKQAQAAITP YYTYNGYIGN NANFILDKNF
     INAIKYDNVK FNGIKLAKTN TIKKVEKYDQ TFKGVSAKGN EASQLQFVVK NNISLKDIQK
     AYGKDLKKEN GKTKEADSGI FYYQNAKKTL GIWFVVDHNR VVEVTVGHTP YKTSK