ID   ISAB_STAAR              Reviewed;         175 AA.
AC   Q6GDG4;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Immunodominant staphylococcal antigen B;
DE   Flags: Precursor;
GN   Name=isaB; OrderedLocusNames=SAR2717;
OS   Staphylococcus aureus (strain MRSA252).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282458;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MRSA252;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IsaB family. {ECO:0000305}.
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DR   EMBL; BX571856; CAG41695.1; -; Genomic_DNA.
DR   RefSeq; WP_001077096.1; NC_002952.2.
DR   AlphaFoldDB; Q6GDG4; -.
DR   SMR; Q6GDG4; -.
DR   PRIDE; Q6GDG4; -.
DR   KEGG; sar:SAR2717; -.
DR   HOGENOM; CLU_119552_0_0_9; -.
DR   OMA; WYKYNGY; -.
DR   OrthoDB; 1536818at2; -.
DR   Proteomes; UP000000596; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Secreted; Signal.
FT   SIGNAL          1..36
FT                   /evidence="ECO:0000250"
FT   CHAIN           37..175
FT                   /note="Immunodominant staphylococcal antigen B"
FT                   /id="PRO_0000272668"
SQ   SEQUENCE   175 AA;  19509 MW;  329DC946534FAD33 CRC64;
     MNQTTKLCAA TTLALGTLIG ATVVGTASPI HQEAQAATTP YYTYHGYIGH NANFIMDKHF
     INAIKYDNVT FNGIKLAKTN ATKKVEKYDQ TFKGVTAKGN EANQLQFIVK NNISLKDIQK
     AYGKDLKKEN NKTKESDSGI FYYQHSKKSL GIWFVVDHNR VVEVTVGHTP YKTSK