APSR1_ARATH
ID APSR1_ARATH Reviewed; 640 AA.
AC A0A178VBJ0; A0A1I9LS38; Q9SD19;
DT 16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT 07-SEP-2016, sequence version 1.
DT 25-MAY-2022, entry version 36.
DE RecName: Full=Protein ALTERED PHOSPHATE STARVATION RESPONSE 1 {ECO:0000303|PubMed:23498857};
GN Name=APSR1 {ECO:0000303|PubMed:23498857};
GN OrderedLocusNames=At3g51290 {ECO:0000312|EMBL:ANM65396.1};
GN ORFNames=F24M12.330 {ECO:0000312|EMBL:CAB62651.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INDUCTION, AND
RP DISRUPTION PHENOTYPE.
RX PubMed=23498857; DOI=10.1016/j.plantsci.2012.12.015;
RA Gonzalez-Mendoza V., Zurita-Silva A., Sanchez-Calderon L.,
RA Sanchez-Sandoval M.E., Oropeza-Aburto A., Gutierrez-Alanis D.,
RA Alatorre-Cobos F., Herrera-Estrella L.;
RT "APSR1, a novel gene required for meristem maintenance, is negatively
RT regulated by low phosphate availability.";
RL Plant Sci. 205:2-12(2013).
CC -!- FUNCTION: Required for the coordination of cell differentiation and
CC cell elongation in the root tip (PubMed:23498857). Required for the
CC coordination of cell processes necessary for correct root growth in
CC response to phosphate starvation, through the modulation of the auxin
CC transporter protein PIN7 (PubMed:23498857).
CC {ECO:0000269|PubMed:23498857}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:23498857}.
CC -!- TISSUE SPECIFICITY: Expressed in the root tip of primary and lateral
CC roots, specifically in the meristematic region, including the quiescent
CC center and lateral root cap cells. {ECO:0000269|PubMed:23498857}.
CC -!- INDUCTION: Down-regulated by phosphate deficiency.
CC {ECO:0000269|PubMed:23498857}.
CC -!- DISRUPTION PHENOTYPE: Defects in primary root elongation and enhanced
CC root hair elongation. {ECO:0000269|PubMed:23498857}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB62651.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL132980; CAB62651.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; ANM65396.1; -; Genomic_DNA.
DR PIR; T45760; T45760.
DR RefSeq; NP_001327368.1; NM_001339498.1.
DR AlphaFoldDB; A0A178VBJ0; -.
DR SMR; A0A178VBJ0; -.
DR STRING; 3702.AT3G51290.2; -.
DR ProteomicsDB; 201476; -.
DR EnsemblPlants; AT3G51290.3; AT3G51290.3; AT3G51290.
DR GeneID; 824292; -.
DR Gramene; AT3G51290.3; AT3G51290.3; AT3G51290.
DR KEGG; ath:AT3G51290; -.
DR PRO; PR:A0A178VBJ0; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; A0A178VBJ0; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR006868; DUF630.
DR InterPro; IPR006867; DUF632.
DR Pfam; PF04783; DUF630; 1.
DR Pfam; PF04782; DUF632; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Nucleus; Reference proteome.
FT CHAIN 1..640
FT /note="Protein ALTERED PHOSPHATE STARVATION RESPONSE 1"
FT /id="PRO_0000448355"
FT REGION 60..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 336..371
FT /evidence="ECO:0000255"
FT COMPBIAS 66..89
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..133
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 640 AA; 71722 MW; 4FCF4DD073FCD8E8 CRC64;
MGCCQSRIDS KEIVSRCKAR KRYLKHLVKA RQTLSVSHAL YLRSLRAVGS SLVHFSSKET
PLHLHHNPPS PSPPPPPPPR PPPPPLSPGS ETTTWTTTTT SSVLPPPPPP PPPPPPPSST
WDFWDPFIPP PPSSSEEEWE EETTTATRTA TGTGSDAAVT TAPTTATPQA SSVVSGFSKD
TMTTTTTGSE LAVVVSRNGK DLMEIIKEVD EYFLKAADSG APLSSLLEIS TSITDFSGHS
KSGKMYSSSN YECNLNPTSF WTRGFAPSKL SEYRNAGGVI GGNCIVGSHS STVDRLYAWE
KKLYQEVKYA ESIKMDHEKK VEQVRRLEMK RAEYVKTEKA KKDVEKLESQ LSVSSQAIQS
ASNEIIKLRE TELYPQLVEL VKGLMCMWRS MYESHQVQTH IVQQLKYLNT IPSTEPTSEL
HRQSTLQLEL EVQQWHHSFC NLVKAQRDYI QSLTGWLRLS LFQFSKNPLV RSSYESKIYS
FCEEWHLAID RIPDKVASEG IKSFLTAVHG IVAQQADEHK QKKRTESMLK DFEKKSASLR
ALESKYSPYS VPESRKKNPV IEKRVKVEML KGKAEEEKSK HEKSVSVTRA MTLNNLQMGF
PHVFQAMVGF SSVCMQAFES VYNQAKSIGE DQEEVKRLLP
