APT1_MAIZE
ID APT1_MAIZE Reviewed; 2605 AA.
AC K7VLR4; Q4JQG0;
DT 01-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2013, sequence version 1.
DT 25-MAY-2022, entry version 37.
DE RecName: Full=Protein ABERRANT POLLEN TRANSMISSION 1 {ECO:0000303|PubMed:16299389};
DE Flags: Precursor;
GN Name=APT1 {ECO:0000303|PubMed:16299389};
GN ORFNames=ZEAMMB73_995624 {ECO:0000312|EMBL:AFW88363.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000312|Proteomes:UP000007305};
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, DISRUPTION PHENOTYPE, TISSUE
RP SPECIFICITY, AND SUBCELLULAR LOCATION.
RC STRAIN=cv. B73 Inbred;
RX PubMed=16299389; DOI=10.1534/genetics.105.050237;
RA Xu Z., Dooner H.K.;
RT "The maize aberrant pollen transmission 1 gene is a SABRE/KIP homolog
RT required for pollen tube growth.";
RL Genetics 172:1251-1261(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73;
RX PubMed=19965430; DOI=10.1126/science.1178534;
RA Schnable P.S., Ware D., Fulton R.S., Stein J.C., Wei F., Pasternak S.,
RA Liang C., Zhang J., Fulton L., Graves T.A., Minx P., Reily A.D.,
RA Courtney L., Kruchowski S.S., Tomlinson C., Strong C., Delehaunty K.,
RA Fronick C., Courtney B., Rock S.M., Belter E., Du F., Kim K., Abbott R.M.,
RA Cotton M., Levy A., Marchetto P., Ochoa K., Jackson S.M., Gillam B.,
RA Chen W., Yan L., Higginbotham J., Cardenas M., Waligorski J., Applebaum E.,
RA Phelps L., Falcone J., Kanchi K., Thane T., Scimone A., Thane N., Henke J.,
RA Wang T., Ruppert J., Shah N., Rotter K., Hodges J., Ingenthron E.,
RA Cordes M., Kohlberg S., Sgro J., Delgado B., Mead K., Chinwalla A.,
RA Leonard S., Crouse K., Collura K., Kudrna D., Currie J., He R.,
RA Angelova A., Rajasekar S., Mueller T., Lomeli R., Scara G., Ko A.,
RA Delaney K., Wissotski M., Lopez G., Campos D., Braidotti M., Ashley E.,
RA Golser W., Kim H., Lee S., Lin J., Dujmic Z., Kim W., Talag J., Zuccolo A.,
RA Fan C., Sebastian A., Kramer M., Spiegel L., Nascimento L., Zutavern T.,
RA Miller B., Ambroise C., Muller S., Spooner W., Narechania A., Ren L.,
RA Wei S., Kumari S., Faga B., Levy M.J., McMahan L., Van Buren P.,
RA Vaughn M.W., Ying K., Yeh C.-T., Emrich S.J., Jia Y., Kalyanaraman A.,
RA Hsia A.-P., Barbazuk W.B., Baucom R.S., Brutnell T.P., Carpita N.C.,
RA Chaparro C., Chia J.-M., Deragon J.-M., Estill J.C., Fu Y., Jeddeloh J.A.,
RA Han Y., Lee H., Li P., Lisch D.R., Liu S., Liu Z., Nagel D.H., McCann M.C.,
RA SanMiguel P., Myers A.M., Nettleton D., Nguyen J., Penning B.W.,
RA Ponnala L., Schneider K.L., Schwartz D.C., Sharma A., Soderlund C.,
RA Springer N.M., Sun Q., Wang H., Waterman M., Westerman R., Wolfgruber T.K.,
RA Yang L., Yu Y., Zhang L., Zhou S., Zhu Q., Bennetzen J.L., Dawe R.K.,
RA Jiang J., Jiang N., Presting G.G., Wessler S.R., Aluru S.,
RA Martienssen R.A., Clifton S.W., McCombie W.R., Wing R.A., Wilson R.K.;
RT "The B73 maize genome: complexity, diversity, and dynamics.";
RL Science 326:1112-1115(2009).
CC -!- FUNCTION: May be involved in membrane trafficking. Required for tip
CC growth in pollen tubes and root hairs. {ECO:0000269|PubMed:16299389}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q6IMT0}. Golgi
CC apparatus {ECO:0000269|PubMed:16299389}.
CC -!- TISSUE SPECIFICITY: Mature pollen-specific.
CC {ECO:0000269|PubMed:16299389}.
CC -!- DISRUPTION PHENOTYPE: Severe pollen transmission deficit due to altered
CC pollen tubes that are short and twisted. {ECO:0000269|PubMed:16299389}.
CC -!- SIMILARITY: Belongs to the SABRE family. {ECO:0000305}.
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DR EMBL; DQ020097; AAY85656.1; -; Genomic_DNA.
DR EMBL; DQ020098; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM000785; AFW88363.1; -; Genomic_DNA.
DR AlphaFoldDB; K7VLR4; -.
DR STRING; 4577.GRMZM2G448687_P01; -.
DR PaxDb; K7VLR4; -.
DR PRIDE; K7VLR4; -.
DR MaizeGDB; 9018755; -.
DR eggNOG; KOG1910; Eukaryota.
DR Proteomes; UP000007305; Unplaced.
DR ExpressionAtlas; K7VLR4; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IDA:UniProtKB.
DR GO; GO:0048868; P:pollen tube development; IMP:UniProtKB.
DR InterPro; IPR045167; FMP27.
DR InterPro; IPR019443; FMP27_C.
DR InterPro; IPR019441; FMP27_GFWDK_dom.
DR PANTHER; PTHR15678; PTHR15678; 1.
DR Pfam; PF10351; Apt1; 1.
DR SMART; SM01214; Fmp27_GFWDK; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; Glycoprotein; Golgi apparatus; Reference proteome;
KW Secreted; Signal.
FT SIGNAL 1..43
FT /evidence="ECO:0000255"
FT CHAIN 44..2605
FT /note="Protein ABERRANT POLLEN TRANSMISSION 1"
FT /evidence="ECO:0000255"
FT /id="PRO_0000432483"
FT REGION 137..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 305..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1761..1818
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2269..2312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2332..2361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2574..2605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1765..1808
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2269..2299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2345..2361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2587..2605
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 232
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 320
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 348
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 516
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 587
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 628
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 696
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 779
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 1171
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 1318
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 1459
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 1791
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 1810
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 2003
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 2280
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 2291
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 2468
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 2564
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CONFLICT 247
FT /note="Q -> P (in Ref. 1; AAY85656)"
FT /evidence="ECO:0000305"
FT CONFLICT 820
FT /note="D -> DE (in Ref. 1; AAY85656)"
FT /evidence="ECO:0000305"
FT CONFLICT 842..845
FT /note="AQKK -> RHKRS (in Ref. 1; AAY85656)"
FT /evidence="ECO:0000305"
FT CONFLICT 1043
FT /note="S -> P (in Ref. 1; AAY85656)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 2605 AA; 291341 MW; E0DC18BFE0F588D4 CRC64;
MMLGLVQLLV GFVVAWEAVE LVLRHGLLLS VFKLAILAAL AAAAGCVAII FFARAVAWVL
QRAAKLSIGC RSYGFNYLRD ITISSPKGAV ESICIGEIRL GLRKPITQLG FTVLTHGPIL
QLQISDLDVV LRQPVKSTNK KKPAPRKPIS TTTAKAKGKS KGQVKWRLIT SMASLLSLSI
VELRLKAPKA ALGIKDLKTD ISKTGGLDPV LNVQVNIIPL FVQALDSDSI GNNTLVFSKL
DWWVSGQYCS AMDTSDHSSF LFEDISLSCD LHQRDKAIRV KNLDLMLGPI VVNLEEKLLA
KKKPSASTVA EQKDEPSVDN KSAARSEGGK LASLNKKISM FPEKVSFNMS KLVLKFLPKD
HGLSINNEIG SISLRCTRLQ PQDFGEVTTH IRLETDVTEI HLLMDGATSV LEVVKVSTVV
SANIPSQPAL PVQAEVDIKI SGFQCNLIVS RIKPLIRINS DKKKPLVLHE NPQQKKAPKE
KLALSLACTM SVPELTLVLH SLDDVPLYHC IFQSANVSAS KMIDRGTQLH GKLGDLKFLV
PSKHQQSMKE GASGTLLHIS HSTLDLEQND PGQDNDEDHA KSAISVNISG IRMHFCFSYL
ESLCATAMSY KVFMKSILPP KKRSVQENAS QKSTKKAKRA LLLKINVAQC SIVYDGEMRL
EDMSIADPKR VNFGSQGGRV VIINEANGSP RMAYVNSTSL PDHKNVHFST SLEIYQFGVS
LNKAKHTMQV ELENFRLTHK EDQLDNKPVE ETKLFDVRKA KFVQRSGGLN DIAACSLINV
TDIAVRWEPD PYLELLEVAT RLKSVLHRMK LQNSVTEVKD NIEHGYSFQK GITLRPWSAR
KAQKKRESVI AIDLESLKIS GELADGVEAM ITVGYIFSEN AKIGVLVEGI SVSFCGAWIL
KSSRMQLSRI PISVSDSNSD KKLQSAAACD WVIQCRDVNI CLPFRLQLRA IDDAVEDTLR
AFKLISAAKT SVLFPEKKSS TTSSKKSKPK STAFRYVRII VRDLIAEIEE EPMQGWLDEH
MILMKNVFCE STVRLNLLDE LSSGKNKDSP KAKLDSSEKN SGCPDVDAYV PGTHSIEKLR
EEIYRQAFQS YYQACQKLPV SEGSGACSSG FQSGFKMSTR RASVMSVCAK DVDVSLSKID
GGDEGMISFI KSLDPVCDKD DIPFSRLYGS NFSLKTRSLS AYLRDYTFPL FSGTNGKCDG
RLVLGQQATC FQPQARQDVY VGKWWRVNLL RSATGYTPPM KTYADIPLYF KKAEVSFGVG
YEPVFADVSY AFTCALRRAN LAKRWYFERP EPPRRERSLP WWDDMRNYIH GKFKLCFNET
KWHLPASTSP YEKLDELLII TDFMEIHYVD GYVSLSSKYL RVYLTSLESL AKKSSLEIPH
HPAIPFLETP SFFMDISIEW GCDSGNPMDH FIFALPAEGK PRDKVFDAFR STSLSLKWSF
SLKPYTTEPI EHQKKSNLNT TAPTVNVGVH DLAWLMKWWN LVFLPPHKLR LFSRFPRFGV
PRFVRSGNLP LDRVMTEQCI RFDAMQLQIN NMPLQADDPA KGLTLHFTKF RYEIAFSRGK
QIFTFDCKRE PLDLVYQGID LHLLKVFINR IPESSTSMDS KIENKVLQTK DKDSLGCEKG
KKKTSPTEKS RDDGFFLYSD YFTIRKQTPK ADAARLSAWQ EDGRKKTEMP LIKSEFDGGD
ESDHDQSGSD DEGFNVVVAD SCQRVFVYGL KILWNLENRA AVLSWVGGLT QAFQPPKPSP
SRQYTQTKIL EKKQLIKEAE MSKDGALSSV SSTSQPSEPQ QIKSSESPPS NGSGKPDLTS
SSENALKRSN NSDSEEEGTR HFMVNVVQPQ FNLHSEEANG RFLLAAGSGR VMVRSFHSIV
QVGQEMFEKA IGSSNDATGG TGPEMTWSRV ELSVMLEHVQ AHVAPTDVDP GAGIQWLPKI
HRRSSEVKRT GALLERVFMP CQMYFRYTRH KGGTPELKVK PLKELTFNSP DITAGMTSRQ
FQVMMDVLTN LLFARTPKKP KSNLSYPLDN DDDNIEEASD AVVPDGVEEV VLAKIGVEVK
ERARKLLLDD IRALSICGET SHGQSQSPKA NDIAWIVTGS RLMLVKQLKK RLVNVRNGRK
EAYSMLRTAM QKAAQLRLME KEKNKSPSFA MRISVRIKKI VWSMLADGKS FSEAEINDMI
FEFDRDYKDI GIAQLTTKLF VLKNGLANAK SDTVVSPWNP PAEWGKNAML RVNAWQGAPT
GGNPVIESFL VDIYPLKIYL TEAMYRMMWG YFFPGDEQQP QKRQELFKVS TTAGTRRKKN
TSVAETNSPN NQSSKETTFA QKPELRRTSS FDRTWEETVA ESVANELVSQ MEGQTNTQYE
PQDAAKDSKL LRPVRSTRED KKIVEPNELK QSRPQKMMDF RNIKISQVEL QLTYEGLPFA
VSDVRLLMDT FHREDFTGTW ARLFSRVKKH IVWGVLKSVT GMQGKKFKAK SSSQKEPSTA
LISAADFNLS DSDGDEAGSS DQLPAFLKKP SDGAGDGFAT SVKGLFSTQK KKAMAFVLKT
MKGDADHDFH GERSENEIEF SPFARQLTIT KTKKLIRRHT KKLNKSKVHK VTATELEVAE
LPPRAPGYNT DSSSDSSSAE TSPKD
