ID   ISCU_BUCBP              Reviewed;         126 AA.
AC   Q89A18;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Iron-sulfur cluster assembly scaffold protein IscU;
DE   AltName: Full=Sulfur acceptor protein IscU;
GN   Name=nifU; Synonyms=iscU; OrderedLocusNames=bbp_545;
OS   Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=224915;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bp;
RX   PubMed=12522265; DOI=10.1073/pnas.0235981100;
RA   van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F.,
RA   Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J.,
RA   Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
RT   "Reductive genome evolution in Buchnera aphidicola.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
CC   -!- FUNCTION: A scaffold on which IscS assembles Fe-S clusters.
CC       Subsequently gives the nascent cluster to other proteins. It is likely
CC       that Fe-S cluster coordination is flexible as the role of this complex
CC       is to build and then hand off Fe-S clusters (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Forms a heterotetramer with IscS; each subunit of the IscS
CC       dimer contacts an IscU monomer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NifU family. {ECO:0000305}.
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DR   EMBL; AE016826; AAO27243.1; -; Genomic_DNA.
DR   RefSeq; WP_011091644.1; NC_004545.1.
DR   AlphaFoldDB; Q89A18; -.
DR   SMR; Q89A18; -.
DR   STRING; 224915.bbp_545; -.
DR   EnsemblBacteria; AAO27243; AAO27243; bbp_545.
DR   GeneID; 56471079; -.
DR   KEGG; bab:bbp_545; -.
DR   eggNOG; COG0822; Bacteria.
DR   HOGENOM; CLU_079283_5_0_6; -.
DR   OMA; YKNPRNY; -.
DR   OrthoDB; 1793654at2; -.
DR   Proteomes; UP000000601; Chromosome.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR   CDD; cd06664; IscU_like; 1.
DR   InterPro; IPR011339; ISC_FeS_clus_asmbl_IscU.
DR   InterPro; IPR002871; NIF_FeS_clus_asmbl_NifU_N.
DR   PANTHER; PTHR10093; PTHR10093; 1.
DR   Pfam; PF01592; NifU_N; 1.
DR   TIGRFAMs; TIGR01999; iscU; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..126
FT                   /note="Iron-sulfur cluster assembly scaffold protein IscU"
FT                   /id="PRO_0000166183"
SQ   SEQUENCE   126 AA;  13571 MW;  B4B45EEE50F0EACF CRC64;
     MAYSKKVIDH YENPRNVGSF KTIDANVGSG LVGAPACGDV MKLQIKVNKN GIIQDACFKT
     YGCGSAIASS SLVTEWIKGK SLIEAENIKN TNIAEELDLP PVKIHCSILA EDAIKAAITD
     YKNKNK