ID   ISF1_YEAS6              Reviewed;         338 AA.
AC   B5VPK7;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 1.
DT   25-MAY-2022, entry version 27.
DE   RecName: Full=Increasing suppression factor 1;
DE   AltName: Full=Mitochondrial biogenesis regulation protein 3;
GN   Name=ISF1; Synonyms=MBR3; ORFNames=AWRI1631_132220;
OS   Saccharomyces cerevisiae (strain AWRI1631) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=545124;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AWRI1631;
RX   PubMed=18778279; DOI=10.1111/j.1567-1364.2008.00434.x;
RA   Borneman A.R., Forgan A.H., Pretorius I.S., Chambers P.J.;
RT   "Comparative genome analysis of a Saccharomyces cerevisiae wine strain.";
RL   FEMS Yeast Res. 8:1185-1195(2008).
CC   -!- FUNCTION: Could influence the NAM7/UPF1 function, possibly at the level
CC       of mRNA turnover. Participates in mitochondrial biogenesis (By
CC       similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ISF1/MBR1 family. {ECO:0000305}.
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DR   EMBL; ABSV01001816; EDZ70141.1; -; Genomic_DNA.
DR   AlphaFoldDB; B5VPK7; -.
DR   Proteomes; UP000008988; Unassembled WGS sequence.
DR   InterPro; IPR031443; Mbr1.
DR   Pfam; PF17058; MBR1; 2.
PE   3: Inferred from homology;
KW   Phosphoprotein.
FT   CHAIN           1..338
FT                   /note="Increasing suppression factor 1"
FT                   /id="PRO_0000408858"
FT   REGION          50..75
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          267..318
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        267..312
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         119
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P32488"
SQ   SEQUENCE   338 AA;  37136 MW;  34A344D983949D5E CRC64;
     MIASEIFERG VQDPFCQDCD YEDETDVQSF LGSNDLNDFV NSKLASFSFQ NSSKSNNSHH
     SSSTNAGNTS RHIGNHTIGH HLRKIKTAPH HLYGFVPANS TNNSNEPIRP SPRRIRANSS
     TLIHQLSRQS TRQSSLGDAA DSCFDHKCIK PRSRHSSCYG IPTHLYGLEK YVSSELDSLA
     VANDQSNDLT SPLTSVSTPA SNSNSYLNLN SSSAAYPSSY LSNEKNNRLK LISHGKISSN
     NVPGHSGNLN HYHRERTPSN LRRESFSLLS NGSSSSPLQT RNNSYSNSLV KSPSNSSLNT
     SVASSNEESI PHTSNCLEER NPRRKSFIKL SLASSFSN